Who is sponsoring NCT02337634?

NCT02337634 is sponsored by University of Chicago.

What condition does NCT02337634 study?

NCT02337634 studies Pathological Gambling, Gambling Disorder.

What drugs are being tested in NCT02337634?

Interventions: Placebo, Milk Thistle.

What is the status of NCT02337634?

NCT02337634 is currently COMPLETED.

Last reviewed 2024-08-14 · How we verify

Silymarin Treatment of Pathological Gambling: A Double-Blind, Placebo-Controlled Study

NCT02337634 Phase 2 COMPLETED Results posted

The goal of the proposed study is to evaluate the efficacy and safety of silymarin in individuals with gambling disorder. The hypothesis to be tested is that silymarin will be more effective and well tolerated in subjects with gambling disorder compared to placebo. The proposed study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.

Details

Lead sponsor	University of Chicago
Phase	Phase 2
Status	COMPLETED
Enrolment	55
Start date	2015-01
Completion	2022-12

Conditions

Pathological Gambling
Gambling Disorder

Interventions

Placebo
Milk Thistle

Primary outcomes

Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBOCS) — Once every two weeks for the 8 weeks of the study
Every 2 weeks the subject will take the PG-YBOCS for the duration of the 8-week study. At each of these visits the outcome will be assessed, but only one value (change from baseline to week 8) will be reported. The scale itself assesses severity of gambling, with higher scores indicating worse outcomes. The scale includes two subscales: a thought/urge subscale and a behavior subscale. Each subscale contains 5 items to be rated with a score of 0-4. Subscale scores are summed to get a total score. Possible total scores range from 0-40.

Countries

United States