NCT02334345 (EVOSKIN) is a NA clinical trial of Evoskin in Radiation Dermatitis, sponsored by University Hospital, Limoges.

Who is sponsoring NCT02334345?

NCT02334345 is sponsored by University Hospital, Limoges.

What drugs are being tested in NCT02334345?

Interventions in NCT02334345: Evoskin, Trixiera.

What condition does NCT02334345 study?

NCT02334345 studies Radiation Dermatitis.

Is NCT02334345 still recruiting?

NCT02334345 is currently completed. Last updated 27 February 2022.

Last reviewed 2022-02-27 · How we verify

NCT02334345: EVOSKIN

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Skin Protection During Radiotherapy in Patients With Breast Cancer: A Comparative Study of Evoskin® Verus Trixéra®

Completed NA Last updated 27 February 2022

What this trial tests

NA trial testing Evoskin in Radiation Dermatitis in 25 participants. Completed in 17 January 2021.

Timeline

1 January 2015

Primary endpoint
1 November 2015

17 January 2021

Quick facts

Lead sponsor	University Hospital, Limoges
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	25
Start date	1 January 2015
Primary completion	1 November 2015
Estimated completion	17 January 2021
Sites	1 location across France

Drugs / interventions tested

Evoskin — full drug profile →
Trixiera — full drug profile →

Conditions studied

Radiation Dermatitis — all drugs for Radiation Dermatitis →

Sponsor

University Hospital, Limoges

Who can join

18 and older, female only, with Radiation Dermatitis. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Average of the radiation dermatitis intensity
Time frame: at 3 months
Radiation dermatitis will be assessed by means of a spectrophotometer after the patient has received 50Gy

Sponsor's own description

Radiotherapy may cause severe skin changes that significantly interfere with the patient's quality of life and may reduce radiotherapy effectiveness. Many skin care instructions and various topical agents are recommended to help patients in the management of radiation skin reactions, but evidence to support the value of the topical treatments of the irradiated skin is lacking. In the present study we investigated the effects of two topical agents used as supportive care to protect skin during radiotherapy.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The scheme, and regulative mechanism of pyroptosis, ferroptosis, and necroptosis in radiation injury.
Ning J, Chen L, Zeng Y, Xiao G, et al · · 2024 · cited 31× · PMID 38481804 · DOI 10.7150/ijbs.91112
Radiation-induced skin reactions: oxidative damage mechanism and antioxidant protection.
Liu C, Wei J, Wang X, Zhao Q, et al · · 2024 · cited 8× · PMID 39450273 · DOI 10.3389/fcell.2024.1480571

Verify or expand the search:

Other recruiting trials for Radiation Dermatitis

Currently open trials in the same condition.

NCT07086638 — ROS-Scavenging Nanozyme Combined With Thermotherapy Alleviate Radiation Dermatitis in Patients With Head and Neck Cancer · NA · recruiting
NCT07081074 — ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head · NA · recruiting
NCT07064577 — Novel ROS-scavenging Nanoenzymes for the Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer · NA · recruiting
NCT06915857 — Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Pr · Phase 3 · recruiting
NCT06729814 — Prospective Assessment of Acute Skin Toxicities in Breast Cancer Patients Undergoing Retreatment with 40 Gy in 15 Fracti · recruiting

Other University Hospital, Limoges trials

Trials by the same sponsor.

NCT07407101 — Impact of Filtration on Autologous Serum Eye Drops · NA · not yet recruiting
NCT07406425 — Evaluation of Efficacy of Coconut Oil Mouth Care for Non-autonomous Hospitalised Elderly People. · NA · not yet recruiting
NCT07436780 — B Lymphocyte Populations in the Pulmonary Microenvironment of Patients Under Mechanical Ventilation With or Without VAP · not yet recruiting
NCT07331298 — Apparent Diffusion Coefficient of the Intervertebral Disc in Children: Pilot Study · not yet recruiting
NCT07019818 — Esmolol Versus Sufentanil on the Quality of Post-cholecystectomy Recovery Laparoscopic Anaesthesia With Orotracheal Intu · Phase 4 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02334345 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Limoges
Last refreshed: 27 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02334345.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing