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NCT02333396

Improving Communication in the PICU: The Navigate Study

Completed NA Results posted Last updated 26 March 2025
What this trial tests

NA trial testing PICU Supports in Communication in 442 participants. Completed in 28 April 2017.

Timeline
6 April 2015
Primary endpoint
28 April 2017
28 April 2017

Quick facts

Lead sponsorAnn & Robert H Lurie Children's Hospital of Chicago
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposeother
Enrollment442
Start date6 April 2015
Primary completion28 April 2017
Estimated completion28 April 2017
Sites2 locations across United States

Drugs / interventions tested

Conditions studied

Sponsor

Ann & Robert H Lurie Children's Hospital of Chicago

Who can join

Eligibility, any sex, with Communication. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Satisfaction With Decision Making (Percentage of "Excellent" Scores in the Decision Making Domain of the Pediatric Family Satisfaction in the Intensive Care Unit (pFS-ICU) Questionnaire) Primary · 3-5 weeks following PICU discharge

Percentage of "excellent" scores in the decision making domain of the Pediatric Family Satisfaction in the Intensive Care Unit (pFS-ICU) questionnaire; minimum=0, maximum=100, higher score is better outcome

GroupValue95% CI
PICU Supports60.35± 33.35
Educational Brochure56.09± 35.23
Pediatric Family Decision Making Satisfaction in the Intensive Care Unit (pFS-ICU) Secondary · 3-5 weeks following PICU discharge

Measures satisfaction of family who have a child admitted to the Pediatric intensive care unit; Pediatric Family Satisfaction in the Intensive Care Unit (pFS-ICU) questionnaire mean score, range 0-100, higher score is the better outcome

GroupValue95% CI
PICU Supports86.63± 13.28
Educational Brochure82.8± 17.6
Parental Satisfaction in the PICU (Score on the Pediatric Family Satisfaction in the Intensive Care Unit (pFS-ICU) Questionnaire) Secondary · 3-5 weeks after PICU Discharge

Subscale: Satisfaction with Care Score on the Pediatric Family Satisfaction in the Intensive Care Unit (pFS-ICU) questionnaire; minimum=0, maximum=100, higher score is better outcome

GroupValue95% CI
PICU Supports87.22± 13.43
Educational Brochure82.94± 17.59
Parental Satisfaction in the PICU (Score on the Pediatric Family Satisfaction in the Intensive Care Unit (pFS-ICU) Questionnaire) Secondary · 3-5 weeks after PICU Discharge

Subscale: Satisfaction with Decision Making Score on the Pediatric Family Satisfaction in the Intensive Care Unit (pFS-ICU) questionnaire; minimum=0, maximum=100, higher score is better outcome

GroupValue95% CI
PICU Supports85.86± 14.94
Educational Brochure82.59± 19.10
Parental Decision Regret (Decision Regret Scale) Secondary · 3-5 weeks after PICU discharge

Score on the Decision Regret Scale, a 5-item Likert-scale measure of decision regret; minimum=0, maximum=100; higher score indicates more decision regret

GroupValue95% CI
PICU Supports12.61± 19.89
Educational Brochure12.87± 16.09
Parental Anxiety (Anxiety SF8a) Secondary · 3-5 weeks after PICU discharge

Score on the Anxiety Short Form8a, a 8-item Likert-scale measure of anxiety, the higher the score, the worst the anxiety, T-score range of 37.1 - 83.1. A T score of 50 is the average fro the US general population. The SD is 10 with a T-score of 60 being 10 worse than the average and a T-score of 40 being 10 better than the average.

GroupValue95% CI
PICU Supports49.32± 9.78
Educational Brochure49.68± 10.26
Parental Depression (Depression SF8a) Secondary · 3-5 weeks after PICU discharge

Score on the Depression; Depression Short Form 8a, a 8-item Likert-scale measure of depression; the higher the score, the worst the depression, T-score range of 38.2 - 81.3. A T score of 50 is the average fro the US general population. The SD is 10 with a T-score of 60 being 10 worse than the average and a T-score of 40 being 10 better than the average.

GroupValue95% CI
PICU Supports47.71± 8.33
Educational Brochure47.23± 9.18
Parental Impact of Event/Post-Traumatic Distress (Impact of Event Scale-revised) Secondary · 3-5 weeks after PICU discharge

A measure of post-traumatic distress; Score on the Impact of Event Scale-revised, a 22-item Likert-scale measure of post-traumatic distress; scale range from 0 - 88; higher numbers mean higher trauma or distress; units on a scale

GroupValue95% CI
PICU Supports14.02± 16.81
Educational Brochure12.93± 14.32
Parental Health-related Quality of Life (Global Health Scale) Physical Secondary · 3-5 weeks after PICU discharge

Measure of global physical health; Physical - Score on the Global Health scale, a 10 item Likert-scale measure of overall health-related quality of life; the higher the score the worse global health, t-score range of 16.2 - 67.7. A T score of 50 is the average fro the US general population. The SD is 10 with a T-score of 60 being 10 worse than the average and a T-score of 40 being 10 better than the average.

GroupValue95% CI
PICU Supports48.42± 7.50
Educational Brochure48.9± 7.76
Parental Health-related Quality of Life (Global Health Scale) Mental Secondary · 3-5 weeks after PICU discharge

Measure of Global Mental Health; Mental - Score on the Global Health scale, a 10 item Likert-scale measure of overall health-related quality of life; high scores indicate worse mental health; T-score range 21.1 - 67.6. A T score of 50 is the average fro the US general population. The SD is 10 with a T-score of 60 being 10 worse than the average and a T-score of 40 being 10 better than the average.

GroupValue95% CI
PICU Supports50.02± 8.01
Educational Brochure50.92± 7.37
Parental Complicated Bereavement (Grief Scale) Secondary · 3-5 weeks after PICU discharge

Measure of complicated grief in parents after their child's death; Score on the Index of complicated Grief Scale, a 19-item Likert-scale measure of complicated grief; minimum 0, maximum 74; higher numbers mean more complicate grief

GroupValue95% CI
PICU Supports1919 – 19
Educational Brochure1919 – 19
Parent Report of Healthcare Team Satisfaction (Collaboration and Satisfaction About Care Decisions Scale) Secondary · 3-5 weeks after PICU Discharge

Measure of Satisfaction with Healthcare team collaboaration Subscale Collaboration Satisfaction Score of the Collaboration and Satisfaction about Care Decisions scale, 2 items on a 9-item Likert-scale measure of healthcare team communication satisfaction in ICUs, Score range from 2 - 14 with higher numbers meaning more satisfaction

GroupValue95% CI
PICU Supports12.81± 2.01
Educational Brochure12.09± 2.61

Sponsor's own description

The project seeks to study the use of an navigator-based intervention called "PICU Supports." The study will test the impact of PICU Supports during and after PICU discharge on parent outcomes (satisfaction with decision making, decision regret, anxiety, depression, post-traumatic stress, health-related quality of life, and complicated bereavement) and on parent and healthcare team member assessments of communication and team collaboration.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Challenges of Families of Patients Hospitalized in the PICU: A Preplanned Secondary Analysis From the Navigate Dataset.
    Tager JB, Hinojosa JT, LiaBraaten BM, Balistreri KA, et al · · 2024 · cited 9× · PMID 37889100 · DOI 10.1097/pcc.0000000000003385
  2. Associations of Patient and Parent Characteristics With Parental Decision Regret in the PICU: A Secondary Analysis of the 2015-2017 Navigate Randomized Comparative Trial.
    Ashworth RC, Malone JR, Franklin D, Sorce LR, et al · · 2024 · cited 5× · PMID 38727516 · DOI 10.1097/pcc.0000000000003534

Verify or expand the search:

Other recruiting trials for Communication

Currently open trials in the same condition.

Other Ann & Robert H Lurie Children's Hospital of Chicago trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02333396.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing