Clinical And Microbiological Analysis Of Orally Administered Lactobacillus Probiotic Lozenges In Chronic Periodontitis Patients Among Smokers And Non-smokers And Its Correlation With Clinical Parameters - A Clinico-Microbiological Study

NCT02329353 Phase 3 COMPLETED

Periodontitis is one of the most common chronic inflammatory disease with the etiology of bacterial plaque and is associated with a number of putative bacterial species. The periodontal destruction is substantially mediated by the host, driven by the bacterial challenge. The presence of pathogenic bacteria with the absence of so-called "beneficial bacteria" and the susceptibility of the host are the main aetiological factors of periodontal diseases.

Details

Lead sponsor	Next Gen Pharma India Pvt. Ltd.
Phase	Phase 3
Status	COMPLETED
Enrolment	60
Start date	2015-02
Completion	2016-12

Conditions

• Chronic Periodontitis

Interventions

• Lactobacillus brevis CD2 Lozenges

Primary outcomes

• Improvement in Clinical Periodontal Indices — 8 weeks
  Improvement in clinical periodontal indices, namely, Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD)

Countries

India