Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy: a Randomized Clinical Trial

NCT02327923 Phase 4 COMPLETED

Comparison of intraoperative infusion of lidocaine and esmolol in the postoperative requirement of opioid for postoperative pain management after laparoscopic cholecystectomy to decrease opioid related side effects and enhance postoperative recovery with multimodal analgesia approach.

Details

Lead sponsor	B.P. Koirala Institute of Health Sciences
Phase	Phase 4
Status	COMPLETED
Enrolment	90
Start date	2015-01
Completion	2016-04

Conditions

• Gall Stone Disease

Interventions

• Lidocaine
• Esmolol
• Paracetamol
• Lidocaine
• Propofol
• Fentanyl
• Vecuronium
• Atropine
• Ephedrine
• Morphine

Primary outcomes

• Opioid (morphine equivalent) requirement in the first 24 h postoperatively — up to 24 hours postoperatively
  total morphine consumed in the first 24 h postoperatively

Countries

Nepal