Perfusion and Antihypertensive Therapy in Acute Ischemic Stroke (PATIS)

NCT02327793 Phase 2 COMPLETED

The purpose of this study is to provide a description of blood flow changes in the brain after blood pressure lowering drugs are given. This information will be used by physicians to guide blood pressure lowering therapy in stroke patients in the future.

Details

Lead sponsor	University of Alberta
Phase	Phase 2
Status	COMPLETED
Enrolment	65
Start date	2009-06
Completion	2015-08

Conditions

• Stroke, Acute

Interventions

• Nitroglycerin
• Labetalol

Primary outcomes

• Change in Volume of Hypoperfused Tissue — 15-30 minutes
  Change in the volume of hypoperfused tissue, defined as that having a CBF \<19 ml/100g/min, between the acute and the post treatment initiation perfusion weighted scans.

Countries

Canada