Who is sponsoring NCT02325479?

NCT02325479 is sponsored by The Egyptian IVF-ET Center.

What condition does NCT02325479 study?

NCT02325479 studies Infertility.

What drugs are being tested in NCT02325479?

Interventions: Enaoxaprin sodium, tissue culture media.

What is the status of NCT02325479?

NCT02325479 is currently COMPLETED.

Last reviewed 2016-02-17 · How we verify

Local Uterine Application of Low Molecular Weight Heparin (LMWH) in Intra-cytoplasmic Sperm Injection (ICSI) a Randomised Controlled Pilot Study

NCT02325479 Phase 1 COMPLETED

Heparin also has the ability to bind with and modulate a wide variety of proteins, which can influence a number of physiological processes involved in implantation \& trophoblastic development. These processes include adhesion of the blastocyst to the endometrial surface \& trophoblastic differentiation \& invasion. A recent Cochrane review hinted towards research to study the possible effects of the local (uterine), \& NOT SYSTEMIC application of heparin during Assisted reproductive technology (ART). Based on the above evidence the investigators hypothesize that low molecular weight heparin given intrauterine at mock embryo transfer after oocyte pick up will help improve pregnancy rates in patients undergoing ART.

Details

Lead sponsor	The Egyptian IVF-ET Center
Phase	Phase 1
Status	COMPLETED
Enrolment	120
Start date	2015-01
Completion	2015-12

Conditions

Infertility

Interventions

Enaoxaprin sodium
tissue culture media

Primary outcomes

pregnancy rate — 14 days
safety

Countries

Egypt