NCT02321852 (Tribunal-Basel) is a Phase 2 clinical trial of Triflusal in Healthy, sponsored by Prof. Dominique de Quervain, MD.

Who is sponsoring NCT02321852?

NCT02321852 is sponsored by Prof. Dominique de Quervain, MD.

What drugs are being tested in NCT02321852?

Interventions in NCT02321852: Triflusal, Placebo.

Is NCT02321852 still recruiting?

NCT02321852 is currently completed. Last updated 9 November 2015.

Last reviewed 2015-11-09 · How we verify

NCT02321852: Tribunal-Basel

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Randomized Placebo Controlled Phase II Cross Over Study on the Influence of Triflusal on Cognitive Functions in Healthy Participants

Completed Phase 2 Last updated 9 November 2015

What this trial tests

Phase 2 trial testing Triflusal in Healthy in 40 participants. Completed in 1 November 2015.

Timeline

1 January 2015

Primary endpoint
1 November 2015

1 November 2015

Quick facts

Lead sponsor	Prof. Dominique de Quervain, MD
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	basic science
Enrollment	40
Start date	1 January 2015
Primary completion	1 November 2015
Estimated completion	1 November 2015
Sites	1 location across Switzerland

Drugs / interventions tested

Triflusal (TRIFLUSAL) — full drug profile →
Placebo

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Prof. Dominique de Quervain, MD

Who can join

Adults 18 to 40, any sex, with Healthy. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Change in performance in episodic memory task as assessed by a picturial memory task between placebo and verum at two different timepoints
Time frame: Timepoint 1:45 minutes after first medication. Timepoint 2: 24 h after last medication.
Picture task as described in (de Quervain, Kolassa et al. 2007). Number of correctly remembered pictures is counted.
Change in performance in episodic memory task as assessed by a verbal memory task between placebo and verum at two different time points.
Time frame: Timepoint 1:45 minutes after first medication. Timepoint 2: 24 h after last medication.
Verbal task as described in ( de Quervain, Henke et al. 2003). Number of correctly remembered words is counted.

Sponsor's own description

The purpose of this study is to investigate the effects of the eNOS activating agent triflusal on episodic memory and cognitive functions in healthy participants.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Triflusal

Trials testing the same drug.

NCT02904109 — Influence of Triflusal on Cognitive Functions in Subjects Under Chronic Stress · Phase 2 · completed

Other recruiting trials for Healthy

Currently open trials in the same condition.

NCT06707207 — Predicting Future Errors During Skill Performance · recruiting
NCT07169630 — PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) · Phase 1 · recruiting
NCT07499414 — The Effects of the Bile Acid Supplement, 7-keto Lithocholic Acid, on Human Gut Microbiota and Risk Factors for Disease. · NA · recruiting
NCT07496697 — Effects of Electroacupuncture at NP82 and SP15 on Bowel Motility in Healthy Subjects · NA · recruiting
NCT06431932 — Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity · Phase 1, PHASE2 · recruiting

Other Prof. Dominique de Quervain, MD trials

Trials by the same sponsor.

NCT04516603 — Influence of Fampridine on Working Memory in Healthy Subjects · Phase 2 · withdrawn
NCT07191288 — Assessing the Acute Effects of Virtual Reality Interventions on Stress · NA · not yet recruiting
NCT07191275 — Study on the Effect of Transcranial Magnetic Stimulation on the Perception of Emotional Images · NA · recruiting
NCT06047899 — Influence of Luteolin for Two Weeks on Memory in Healthy Subjects · NA · completed
NCT05847933 — Influence of Temporo-occipital Transcranial Magnetic Brain Stimulation on Aversive Episodic Memory Performance · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02321852 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Prof. Dominique de Quervain, MD
Last refreshed: 9 November 2015

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02321852.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing