Evaluating the Effectiveness and Feasibility of Reactive Focal Mass Drug Administration vs. Reactive Case Detection as a Community Level Intervention in Response to a Passively Identified Index Malaria Case in Swaziland (fMDA)

NCT02315690 Phase 3 COMPLETED

This is a cluster randomised controlled trial comparing the impact of two community based malaria interventions: reactive case detection (RACD) vs reactive targeted presumptive treatment (focal mass drug administration, fMDA) on the incidence of malaria in Swaziland.

Details

Lead sponsor	University of California, San Francisco
Phase	Phase 3
Status	COMPLETED
Enrolment	4000
Start date	2015-09
Completion	2017-07

Conditions

• Malaria

Interventions

• dihydroartemisinin-piperaquine (DHAp)
• reactive case detection

Primary outcomes

• Incidence of malaria cases — 2 years
  Cumulative incidence of malaria cases by locality

Countries

Eswatini