Pilot Study of Bicarbonate Injection for Improving Outcome in Patients With Out-of-hospital Cardiac Arrest, Double-blind Randomized Control Trial

NCT02303548 Phase 2 COMPLETED Results posted

A pilot study to evaluate the effect of sodium bicarbonate administration on cardiopulmonary resuscitation results and outcomes in cardiac arrest patient with severe metabolic acidosis.

Details

Lead sponsor	Asan Medical Center
Phase	Phase 2
Status	COMPLETED
Enrolment	50
Start date	2014-10
Completion	2016-02

Conditions

• Cardiac Arrest
• Metabolic Acidosis

Interventions

• Sodium bicarbonate
• Normal saline

Primary outcomes

• Return of Spontaneous Circulation (ROSC) — checked during CPR, duration of ROSC >20 min
  Percentage of Participants with Return of Spontaneous Circulation (ROSC)