Mephedrone and Alcohol Interactions After Single-dose Administration in Humans

NCT02294266 Phase 1 COMPLETED

The purposes of this study are 1) to evaluate the pharmacological effects after oral coadministration of mephedrone and alcohol and 2) determine the pharmacokinetics changes of mephedrone and alcohol concentrations after oral coadministration of mephedrone and alcohol.

Details

Lead sponsor	Parc de Salut Mar
Phase	Phase 1
Status	COMPLETED
Enrolment	12
Start date	2014-12
Completion	2015-03

Conditions

• Amphetamine-Related Disorders
• Alcohol-Related Disorders

Interventions

• Mephedrone and alcohol
• Mephedrone
• Alcohol
• Placebo

Primary outcomes

• Change in drunkenness and drowsiness and effects — From pre-dose (baseline, 0h) to 6h post-dose
  Drunkenness and drowsiness effects will be measured using rate scales (visual analogue scales).

Countries

Spain