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NCT02292745: LAPC-1
Efficacy and Feasibility of Combining FOLFIRINOX and Stereotactic Radiotherapy for Patients With Irresectable Locally Advanced Pancreatic Cancer.
NA trial testing stereotactic radiotherapy in Pancreatic Neoplasms in 53 participants. Completed in 24 May 2018.
24 May 2018
Quick facts
| Lead sponsor | Foundation for Liver Research |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 53 |
| Start date | 2 December 2014 |
| Primary completion | 24 May 2018 |
| Estimated completion | 24 May 2018 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- stereotactic radiotherapy
Conditions studied
- Pancreatic Neoplasms — all drugs for Pancreatic Neoplasms →
Sponsor
Foundation for Liver Research
Who can join
Adults 18 to 75, any sex, with Pancreatic Neoplasms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to investigate whether combining FOLFIRINOX chemotherapy and stereotactic radiotherapy in patients with locally advanced pancreatic cancer leads to an increase in survival.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Current therapeutic strategies for advanced pancreatic cancer: A review for clinicians.
Spadi R, Brusa F, Ponzetti A, Chiappino I, et al · · 2016 · cited 64× · PMID 26862489 · DOI 10.5306/wjco.v7.i1.27 -
Efficacy and feasibility of stereotactic radiotherapy after folfirinox in patients with locally advanced pancreatic cancer (LAPC-1 trial).
Suker M, Nuyttens JJ, Eskens FALM, Haberkorn BCM, et al · · 2019 · cited 50× · PMID 31891135 · DOI 10.1016/j.eclinm.2019.10.013
Verify or expand the search:
- PubMed search for NCT02292745
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT03921957 — Study of the Decrease of Length of Stereotactic Body Radiation Therapy in Lung Cancer · NA · unknown
Other recruiting trials for Pancreatic Neoplasms
Currently open trials in the same condition.
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- NCT07139236 — Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD · recruiting
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- NCT06939023 — Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3) · NA · recruiting
- NCT06953193 — Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia · NA · recruiting
Other Foundation for Liver Research trials
Trials by the same sponsor.
- NCT03120195 — EndoRotor® Ablation of Barrett's Esophagus: Safety and Feasibility Study · NA · completed
- NCT01373684 — PEG-interferon Alfa-2a add-on Study in HBeAg Negative Chronic Hepatitis B Patients · Phase 4 · completed
- NCT01958190 — Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&Sirolimus · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02292745 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Foundation for Liver Research
- Last refreshed: 29 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02292745.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing