Validation of Drug Assays in Various Biological Matrices

NCT02283112 RECRUITING

This study aims to ensure that assays that measure drug concentrations are accurate and precise in different matrices when quantified using high performance liquid chromatography -tandem mass spectrometry (HPLC-MS/MS). The study involves collecting samples of various bodily fluids to quantify antimicrobials, antivirals, oral contraceptives and erectile dysfunction agents. Samples will also be obtained from individuals not receiving these medications for quality control purposes.

Details

Lead sponsor	University of Liverpool
Status	RECRUITING
Enrolment	100
Start date	2014-10
Completion	2027-12-31

Conditions

• Infection

Interventions

• antivirals, antimicrobials, oral contraceptive, erectile dysfunction agents

Primary outcomes

• To measure drug concentrations using high performance liquid chromatography -tandem mass spectrometry (HPLC-MS/MS) (accuracy and precision of assays that measure drug concentrations) — Follow up up to 5 years
  Assay validation

Countries

United Kingdom