NCT02282566

Effect of Protein-nutrition Beverages on Muscle Protein Synthesis in Women

Completed NA Last updated 10 March 2021

What this trial tests

NA trial testing Protein-nutrition beverage in Muscle Protein Synthesis in 48 participants. Completed in 30 March 2017.

Timeline

6 January 2015

Primary endpoint
30 March 2017

30 March 2017

Quick facts

Lead sponsor	PepsiCo Global R&D
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	48
Start date	6 January 2015
Primary completion	30 March 2017
Estimated completion	30 March 2017
Sites	1 location across Canada

Drugs / interventions tested

• Protein-nutrition beverage

Conditions studied

• Muscle Protein Synthesis — all drugs for Muscle Protein Synthesis →

Sponsor

PepsiCo Global R&D — full company profile →

Who can join

Adults 65 to 75, female only, with Muscle Protein Synthesis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study investigates whether a protein-nutrition beverage can increase muscle protein synthesis to a similar magnitude as a control beverage.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Leucine, Not Total Protein, Content of a Supplement Is the Primary Determinant of Muscle Protein Anabolic Responses in Healthy Older Women.
   Devries MC, McGlory C, Bolster DR, Kamil A, et al · · 2018 · cited 96× · PMID 29901760 · DOI 10.1093/jn/nxy091
2. Protein leucine content is a determinant of shorter- and longer-term muscle protein synthetic responses at rest and following resistance exercise in healthy older women: a randomized, controlled trial.
   Devries MC, McGlory C, Bolster DR, Kamil A, et al · · 2018 · cited 80× · PMID 29529146 · DOI 10.1093/ajcn/nqx028