Carboplatin AUC-10 With Early PET Scanning in Metastatic Seminoma (Car-PET)

NCT02272816 PHASE2 COMPLETED Results posted

This study evaluated the safety, efficacy and toxicity of carboplatin area under the curve (AUC)-10 in metastatic seminoma to see if, by using fluoro-deoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) to assess metabolic response, the number of patients requiring 4 cycles can be reduced. Carboplatin AUC-10 was given every 21 days. A PET-CT scan was carried out on day 17-21 of the first cycle. If the PET - CT scan showed a complete response patients received 3 cycles of treatment. If the PET - CT scan did not show a complete response patients received 4 cycles of treatment. After treatment, patients were followed up for 2 years.

Details

Lead sponsor	Barts & The London NHS Trust
Phase	PHASE2
Status	COMPLETED
Enrolment	48
Start date	Mon Feb 13 2012 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Oct 13 2017 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Metastatic Seminoma

Interventions

• Carboplatin AUC-10

Countries

United Kingdom