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NCT02268071
Stopping Antihypertensive Treatment amOng Hypertensive Patients in Primary Care (STOP-Trial)
NA trial testing Antihypertensive treatment will be stopped for 1 year unless hypertension recurrence in Hypertension in 403 participants. Completed in 21 October 2020.
21 October 2020
Quick facts
| Lead sponsor | Central Hospital, Nancy, France |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 403 |
| Start date | 10 March 2015 |
| Primary completion | 21 October 2020 |
| Estimated completion | 21 October 2020 |
| Sites | 24 locations across France |
Drugs / interventions tested
- Antihypertensive treatment will be stopped for 1 year unless hypertension recurrence — full drug profile →
Conditions studied
- Hypertension — all drugs for Hypertension →
Sponsor
Central Hospital, Nancy, France
Who can join
18 and older, any sex, with Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The STOP-Trial is a prospective multicenter nonrandomized open study on grade I hypertension, performed by General practitioners. The study will be conducted in parallel in the Clinical Investigation Center Plurithematic (CIC-P)1433 of Nancy (the study coordinating center) by the general practitioners investigators of the CIC-P. The main purpose of the study is to determine the factors associated with the rate of patients remaining normotensive one year after stopping their antihypertensive monotherapy or low dose dual therapy: * white coat hypertension * primary diagnosis by home blood pressure measurements (HBPM) /ambulatory blood pressure measurements (ABPM) /clinical measure * initial blood pressure level * compliance * therapeutic class versus others * age * gender * weight variation * modification of lifestyle * concomitant treatments and associated substances * ... The primary endpoint will be the rate of normotensive patients at one year (i.e. HBPM values \<135/85 mmHg).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Stopping antihypertensive Treatment amOng hypertensive patients in Primary care: the STOP-Trial.
Boivin JM, Ferreira JP, Lopez-Sublet M, Duarte K, et al · · 2026 · cited 1× · PMID 40838798 · DOI 10.1093/eurjpc/zwaf511
Verify or expand the search:
- PubMed search for NCT02268071
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Central Hospital, Nancy, France trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02268071 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Central Hospital, Nancy, France
- Last refreshed: 22 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02268071.
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