Rituximab and Belimumab for Lupus Nephritis (CALIBRATE)

NCT02260934 PHASE2 COMPLETED Results posted

In this experimental study, researchers will try to find out if treatment of lupus nephritis with a combination of rituximab and cyclophosphamide (CTX), or a combination of rituximab and CTX followed by treatment with belimumab is safe and if this drug combination can block the immune system attacks.

Details

Lead sponsor	National Institute of Allergy and Infectious Diseases (NIAID)
Phase	PHASE2
Status	COMPLETED
Enrolment	43
Start date	Thu Jul 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Feb 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Lupus Nephritis

Interventions

• Rituximab
• Cyclophosphamide
• Prednisone
• Methylprednisolone
• Diphenhydramine
• Acetaminophen
• Rituximab
• Cyclophosphamide
• Prednisone
• Methylprednisolone

Countries

United States