Last reviewed · How we verify
Metformin and Sitagliptin Therapy for Adult Patients With Type 2 Diabetes Admitted to the General Medical Unit
The purpose of this study is to test whether a combination of two pills commonly used to treat outpatient diabetes called metformin and sitagliptin (januvia) could provide successful control of blood sugar levels in patients with type 2 diabetes during hospitalization for the treatment of a general medical condition. Both metformin and sitagliptin are currently approved by the Food and Drug Administration for the treatment of type 2 diabetes, but little experience exists for their use in hospitalized patients. The current standard practice is to use insulin injections to control blood sugar in hospitalized patients with type 2 diabetes. This study will compare the use of metformin tablets twice per day along with sitagliptin tablets once per day with daily insulin injections in patients with type 2 diabetes during hospitalization, and will study how well the blood sugar levels are controlled.
Details
| Lead sponsor | Rush University Medical Center |
|---|---|
| Phase | Phase 4 |
| Status | WITHDRAWN |
| Start date | 2014-10 |
| Completion | 2015-05 |
Conditions
- Type 2 Diabetes Mellitus
Interventions
- metformin and sitagliptin
- insulin glargine and insulin lispro
- metformin and sitagliptin
- insulin glargine and insulin lispro
Primary outcomes
- mean blood glucose for the duration of the hospital stay — duration of hospital stay
Participants will be followed for the duration of the hospital stay, an expected average of 5 days.