Efficacy and Safety of Warfarin Anticoagulation for Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients After Laparoscopic Splenectomy and Azygoportal Disconnection for Portal Hypertension (ESWAPH)

NCT02247414 Phase 4 COMPLETED

The purpose of this study is to determine whether Warfarin Anticoagulation are effective and safe in Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients after Laparoscopic Splenectomy and Azygoportal Disconnection for Portal Hypertension

Details

Lead sponsor	Yangzhou University
Phase	Phase 4
Status	COMPLETED
Enrolment	124
Start date	2014-09
Completion	2018-04

Conditions

• Cirrhosis
• Hypertension
• Status;Splenectomy
• Venous Thrombosis

Interventions

• Warfarin
• Dipyridamole
• Aspirin
• Low Molecular Weight Heparin

Primary outcomes

• Proportions of patients who will suffer PVT or spleno-mesenteric thrombosis between oral anticoagulant Warfarin with dipyridamole group and oral Aspirin with dipyridamole group during the study period of 3 year from randomization — 3 years

Countries

China