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NCT02243384
Laparoscopic Hepatectomy and Radiofrequency Ablation in the Treatment of Early Hepatocellular Carcinoma
NA trial testing Laparoscopic Hepatectomy in Hepatocellular Carcinoma in 150 participants. Completed in 1 October 2021.
1 January 2021
Quick facts
| Lead sponsor | ChenJian |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 150 |
| Start date | 1 September 2014 |
| Primary completion | 1 January 2021 |
| Estimated completion | 1 October 2021 |
| Sites | 1 location across China |
Drugs / interventions tested
- Laparoscopic Hepatectomy
- Radiofrequency Ablation
Conditions studied
- Hepatocellular Carcinoma — all drugs for Hepatocellular Carcinoma →
Sponsor
ChenJian
Who can join
Adults 18 to 70, any sex, with Hepatocellular Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this research is to compare short-term and long-term efficacy of laparoscopic hepatectomy and radiofrequency ablation in the Treatment of early hepatocellular carcinoma, and provide the evidence for the choice of surgical method from the pathology and cytology.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Laparoscopic hepatectomy versus radiofrequency ablation for hepatocellular carcinoma: a systematic review and meta-analysis.
Li X, Wu YS, Chen D, Lin H. · · 2019 · cited 20× · PMID 31417314 · DOI 10.2147/cmar.s189777 -
Laparoscopic liver resection versus radiofrequency ablation for small hepatocellular carcinoma: randomized clinical trial.
Song J, Cao L, Ma K, Li J, et al · · 2024 · cited 10× · PMID 38650579 · DOI 10.1093/bjs/znae099 -
Precision oncology: The role of minimally-invasive ablation therapy in the management of solid organ tumors.
Fazlollahi F, Makary MS. · · 2025 · cited 2× · PMID 39876886 · DOI 10.4329/wjr.v17.i1.98618
Verify or expand the search:
- PubMed search for NCT02243384
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Laparoscopic Hepatectomy
Trials testing the same drug.
- NCT03313648 — A Study of Laparoscopic Hepatectomy Versus RFA in the Treatment of Recurrent HCC · NA · unknown
Other recruiting trials for Hepatocellular Carcinoma
Currently open trials in the same condition.
- NCT06902246 — Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular Carcinoma · Phase 2 · recruiting
- NCT05842174 — Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma · Phase 1, PHASE2 · recruiting
- NCT07417397 — Adjuvant TACE in HCC With High-risk Recurrence Factors · Phase 3 · recruiting
- NCT07317414 — β-alanine in the Treatment of Advanced Hepatocellular Carcinoma · Phase 2 · recruiting
- NCT07148050 — Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimer · Phase 1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02243384 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by ChenJian
- Last refreshed: 2 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02243384.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing