Last reviewed · How we verify
Diagnosis of Demodex Blapharitis and Treatment With Ivermectin Gel 0.1%/ Metronidazole 1%
Blepharitis is a endemic inflammatory disease caused mainly by Demodex folliculorum and Demodex Brevis, This mites are often associated with anaerobic bacteria that produces a skin inflammation, so a intervention that reduces the number of mites and bacteria would be desirable. Ivermectin a macrolid compound have demonstrated activity against scabies and lice in humans and in animals and a single application have show a good response in lice eradication. In this study , investigators will determinate the security and effectiveness of this compound in the eradication of mites
Details
| Lead sponsor | Universidad Nacional de Colombia |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 60 |
| Start date | 2014-10 |
| Completion | 2015-01 |
Conditions
- Chronic Blepharitis
Interventions
- Ivermectin 0.1% Metronidazole 1%
- None intervention
Primary outcomes
- Erradication of Demodex mites — 2 months
Reduction in mites count after treatment compared to baseline data. If mites are not observed in the last visit a complete eradication will be considered. Patients with one or more mites will be considered as a incomplete eradication
Countries
Colombia