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NCT02233348

Neurocognitive and Psychosocial Outcome of Youths With Autism Spectrum Disorder

Completed Last updated 2 September 2021
What this trial tests

trial in Autism Spectrum Disorder in 523 participants. Completed in 31 December 2019.

Timeline
1 January 2015
Primary endpoint
31 December 2019
31 December 2019

Quick facts

Lead sponsorNational Taiwan University Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment523
Start date1 January 2015
Primary completion31 December 2019
Estimated completion31 December 2019
Sites1 location across Taiwan

Conditions studied

Sponsor

National Taiwan University Hospital

Who can join

Adults 10 to 25, any sex, with Autism Spectrum Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Autism spectrum disorders (ASD) is a common childhood-onset, multi-factorial, highly heritable, clinically and genetically heterogeneous, neurodevelopmental disorder. Due to its high prevalence and severe lifelong impairment without effective prevention and treatment, there is a dearth of investigating its pathogenesis, longitudinal outcome, and biomarkers (endophenotypes). The ultimate goals of this 5-year project are to prospectively investigate the outcome and changes of psychosocial and neurocognitive functions of a cohort of probands with ASD at adolescence and young adulthood as the primary aim; and to test whether structural and functional brain connectivity can be effective endophenotypes of ASD using the unaffected sibling and follow-up designs as the secondary aims.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Development of frontoparietal connectivity predicts longitudinal symptom changes in young people with autism spectrum disorder.
    Lin HY, Perry A, Cocchi L, Roberts JA, et al · · 2019 · cited 39× · PMID 30755585 · DOI 10.1038/s41398-019-0418-5
  2. Exploring social emotion processing in autism: evaluating the reading the mind in the eyes test using network analysis.
    Li TS, Gau SS, Chou TL. · · 2022 · cited 3× · PMID 35241030 · DOI 10.1186/s12888-022-03773-x
  3. Developmental changes of visuospatial working memory in autistic children and adolescents.
    Lin YJ, Wu YY, Tsai WC, Chang JC, et al · · 2025 · PMID 40685389 · DOI 10.1017/s0033291725000133

Verify or expand the search:

Other recruiting trials for Autism Spectrum Disorder

Currently open trials in the same condition.

Other National Taiwan University Hospital trials

Trials by the same sponsor.

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Data sources for this page

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