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Thiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural Cambodia
The purpose of this study is to determine whether consumption of thiamin fortified fish sauce over 6 months increases the thiamin status of women to a level consistent with a low risk of infantile beriberi. The investigators hypothesize that consumption of thiamin-fortified fish sauce will increase red blood cell thiamin concentrations, an indicator of thiamin status, in women consuming thiamin-fortified fish sauce, while concentrations will not change in women consuming a placebo fish sauce that does not contain thiamin.
Details
| Lead sponsor | University of British Columbia |
|---|---|
| Phase | Phase 1 |
| Status | COMPLETED |
| Enrolment | 366 |
| Start date | 2014-10 |
| Completion | 2016-04 |
Conditions
- Thiamin Deficiency
Interventions
- Thiamin fortified fish sauce (low concentration)
- Thiamin fortified fish sauce (higher concentration)
- Placebo fish sauce
Primary outcomes
- Erythrocyte thiamin diphosphate — Baseline (t=0), Endline (t=6 months)
Measurement at baseline and endline for all women. Blood samples from infants of women recruited in the pregnancy cohort will be collected at endline only.
Countries
Cambodia