Prospective, Double-blind, Randomized Study to Evaluate a Single Shot Adductor Canal Nerve Block Versus Femoral Nerve Block Combined With LIA (Local Infiltration Analgesia): Early Postoperative Period Functional Outcomes After Total Knee Replacement (ACB)

NCT02218814 NA COMPLETED

The purpose of this study is to determine if patients undergoing a Total Knee Arthroplasty who receive a single shot Adductor Canal nerve block and local infiltration will have improved functional outcomes compared to individuals who receive a femoral nerve block and local infiltration during the first 24 hours post surgery.

Details

Lead sponsor	George Macrinici
Phase	NA
Status	COMPLETED
Enrolment	106
Start date	2014-08
Completion	2016-01

Conditions

• Arthroplasty, Replacement, Knee
• Nerve Block

Interventions

• Adductor Canal Block, Bupivacaine
• Femoral Nerve Block, Bupivacaine

Primary outcomes

• Quadriceps muscle strength (MVIC) difference between the ACB and FNB after total knee arthroplasty. — Baseline, 6, 24, 48 hours and at 6 month after nerve block performance
  Maximum Voluntary Isovolumetric Contraction (MVIC) measured in Newtons of the quadriceps muscle normalized to body mass index (N•m/kg). The 6 hours post procedure percent of baseline is considered the primary clinical success criterion variable of this study.

Countries

United States