L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection: a Double-blind Randomized Controlled Trial.

NCT02216253 NA COMPLETED

This study will include women who will undergo pelvic reconstructive surgery and/or anti-incontinence sling procedures. Patients will be randomized to the combination of L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract in tablet or placebo twice a day during the seven days before and after surgery (total of 14 days). In this randomized, double-blind study, the investigators will assess treatment of clinically suspected or culture-proven urinary tract infections within 3 weeks of surgery (primary outcome), and risk factors for treatment for postoperative urinary tract infections (secondary outcomes) between the two study groups.

Details

Lead sponsor	IRCCS San Raffaele
Phase	NA
Status	COMPLETED
Enrolment	150
Start date	2014-10

Conditions

• Urinary Tract Infection
• Pelvic Organ Prolapse
• Urinary Incontinence

Interventions

• L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract
• Placebo

Primary outcomes

• Treatment for urinary tract infection after surgery. — 3 weeks after surgery.
  To assess any treatment received for clinically suspected or culture-proven urinary tract infection within 3 weeks of surgery.

Countries

Italy