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Effects of Low Dose Aspirin Pre-treatment on Platelet Activation Undergoing Off-pump Coronary Artery Bypass Surgery
Platelet activation after off pump coronary artery bypass (OPCAB) surgery may affect thrombus formation. The purpose of this study is to assess the effects of preoperative continuation of aspirin on platelet activation after off pump coronary artery bypass surgery.
Details
| Lead sponsor | Seoul National University Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 48 |
| Start date | 2014-07 |
| Completion | 2015-09 |
Conditions
- Coronary Artery Disease
Interventions
- aspirin continuation
- aspirin discontinuation
Primary outcomes
- change from baseline in platelet p-selectin at 48 hours after operation — after induction of anesthesia(baseline), at the time of end of operation, 24 hour after operation, 48hr after operation
Primary outcome is expression of platelet p-selectin measured by flowcytometry 48 hours after OPCAB surgery in both groups.
Countries
South Korea