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NCT02179034
Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1
Phase 1 trial testing Nicotine in Nicotine Dependence, Other Tobacco Product in 59 participants. Completed in 12 June 2017.
18 July 2016
Quick facts
| Lead sponsor | Yale University |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | other |
| Enrollment | 59 |
| Start date | 23 October 2014 |
| Primary completion | 18 July 2016 |
| Estimated completion | 12 June 2017 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Nicotine (NICOTINE) — full drug profile →
- Low Dose Menthol
- High Dose Menthol
Conditions studied
- Nicotine Dependence, Other Tobacco Product — all drugs for Nicotine Dependence, Other Tobacco Product →
Sponsor
Yale University
Who can join
Adults 18 to 20, any sex, with Nicotine Dependence, Other Tobacco Product. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is to examine if inhaled doses of menthol that produce low and high cooling effects change the appeal of e-cigarettes containing low and high doses of nicotine in adolescent smokers. The hypothesis is that the combination of nicotine and menthol, when compared with menthol or nicotine alone, will result in greater increase in liking of an e-cigarette and greater reduction in nicotine withdrawal.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT02179034
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06027723 — Nicotine and Pavlovian Bias · EARLY_PHASE1 · unknown
- NCT03634839 — Effects of E-cigarette Flavors on Youth TCORS 2.0 · Phase 1 · completed
Other recruiting trials for Nicotine Dependence, Other Tobacco Product
Currently open trials in the same condition.
- NCT06862050 — BREATHE Free: a Pilot Feasibility Trial · NA · recruiting
Other Yale University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02179034 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yale University
- Last refreshed: 4 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02179034.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing