NCT02152865 is a NA clinical trial of Lupeol in Acne, sponsored by Seoul National University Hospital.

Who is sponsoring NCT02152865?

NCT02152865 is sponsored by Seoul National University Hospital.

What drugs are being tested in NCT02152865?

Interventions in NCT02152865: Lupeol, Control vehicle.

Is NCT02152865 still recruiting?

NCT02152865 is currently completed. Last updated 28 May 2014.

Last reviewed 2014-05-28 · How we verify

NCT02152865

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Trial of Lupeol for Mild-moderate Acne

Completed NA Last updated 28 May 2014

What this trial tests

NA trial testing Lupeol in Acne in 25 participants. Completed in 1 May 2014.

Timeline

1 December 2009

Primary endpoint
1 May 2014

1 May 2014

Quick facts

Lead sponsor	Seoul National University Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	25
Start date	1 December 2009
Primary completion	1 May 2014
Estimated completion	1 May 2014
Sites	1 location across South Korea

Drugs / interventions tested

Lupeol — full drug profile →
Control vehicle — full drug profile →

Conditions studied

Acne — all drugs for Acne →

Sponsor

Seoul National University Hospital

Who can join

15 and older, any sex, with Acne. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Acne lesion counts as a measure of efficacy
Time frame: 8 weeks after beginning of applications
Both inflammatory \& non-inflammatory acne lesions of both of their facial sides

Sponsor's own description

For the chemical lupeol isolated from eggplant, we applied it to one side of face, and applied vehicle control to another side for 8 -weeks. The study was performed in a 8-week, randomized controlled, split face fashion. Investigators evaluated safety and efficacy during baseline, 2 weeks, 4weeks, and 8 weeks after beginning of study.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Lupeol Counteracts the Proinflammatory Signalling Triggered in Macrophages by 7-Keto-Cholesterol: New Perspectives in the Therapy of Atherosclerosis.
Saha S, Profumo E, Togna AR, Riganò R, et al · · 2020 · cited 27× · PMID 33062133 · DOI 10.1155/2020/1232816

Verify or expand the search:

Other recruiting trials for Acne

Currently open trials in the same condition.

NCT07366229 — Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne · Phase 2 · recruiting
NCT07013747 — Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne · Phase 1, PHASE2 · recruiting
NCT06989840 — Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne · Phase 1 · recruiting
NCT07368764 — The Suitability of Tience® for Treating Acne Scars · NA · recruiting
NCT06909344 — 577-nm Diode Laser in the Treatment of Non -Inflammatory Acne · NA · recruiting

Other Seoul National University Hospital trials

Trials by the same sponsor.

NCT07262944 — EOI Block in Otoplasty With Rib Cartilage Graft · NA · recruiting
NCT07464210 — Nemtabrutinib, Bortezomib, and Rituximab for WM · Phase 2 · not yet recruiting
NCT07550803 — Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery · NA · not yet recruiting
NCT07522138 — Home-based Self-exercise in Patients With Parkinson's Disease: A Feasibility Study · NA · not yet recruiting
NCT07476651 — Scout Dose of Resin Microspheres · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02152865 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
Last refreshed: 28 May 2014

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02152865.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing