Prevention of Postoperative Bleeding in Femoral Fractures: a Multicenter, Randomized, Controlled, Parallel Clinical Trial to Assess the Efficacy of Tranexamic Acid and Fibrin Glue (TRANEXFER)

NCT02150720 Phase 3 COMPLETED

The main hypothesis of this clinical trial is that the use of intra-articular tranexamic acid and the fibrin glue plus usual hemostasis will reduce at least a 25% the postoperative blood loss with respect to usual hemostasis in patients undergoing subcapital femoral fractures.

Details

Lead sponsor	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Phase	Phase 3
Status	COMPLETED
Enrolment	161
Start date	2013-02
Completion	2016-03

Conditions

• Hip Fracture
• Blood Loss

Interventions

• Tranexamic Acid
• Fibrin glue
• Electrocauterization

Primary outcomes

• Blood loss (ml) after surgery — The first postoperative 24h
  The blood lost from the wound will be collected by a drainage system during the first 24 hours postoperatively.

Countries

Spain