NCT02149953

Determination of Glycine Requirement in Pregnancy

Completed NA Last updated 23 September 2020

What this trial tests

NA trial testing Glycine Intake in Pregnancy in 13 participants. Completed in 26 September 2016.

Timeline

19 September 2014

Primary endpoint
26 September 2016

26 September 2016

Quick facts

Lead sponsor	University of British Columbia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	13
Start date	19 September 2014
Primary completion	26 September 2016
Estimated completion	26 September 2016
Sites	1 location across Canada

Drugs / interventions tested

• Glycine Intake

Conditions studied

• Pregnancy — all drugs for Pregnancy →

Sponsor

University of British Columbia

Who can join

Adults 20 to 40, female only, with Pregnancy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is important that pregnant women eat an adequate amount of protein to ensure healthy growth and development of the fetus. Amino acids are the building blocks of the body's protein. Glycine is an amino acid that can be made in the body, but under certain metabolic circumstances (e.g. pregnancy) the body's needs may be higher and thus glycine must be obtained from the diet. Currently, it is not known how much glycine may be needed from the diet during pregnancy. We plan to study dietary glycine requirements in healthy pregnant women, during early and late gestation. We will do this using a modern, safe and quick method.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Glycine, a Dispensable Amino Acid, Is Conditionally Indispensable in Late Stages of Human Pregnancy.
   Rasmussen BF, Ennis MA, Dyer RA, Lim K, et al · · 2021 · cited 19× · PMID 32939556 · DOI 10.1093/jn/nxaa263