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NCT02138721: LoMP

Local Treatment With RP for Newly-diagnosed mPCa

Status unknown NA Last updated 20 December 2023
What this trial tests

NA trial testing Radical Prostatectomy (RP) in Prostatic Neoplasms in 80 participants. Status unknown.

Timeline
28 June 2018
Primary endpoint
31 December 2024
31 December 2024

Quick facts

Lead sponsorUniversity Hospital, Ghent
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment80
Start date28 June 2018
Primary completion31 December 2024
Estimated completion31 December 2024
Sites5 locations across Belgium

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Ghent

Who can join

Adults 18 to 85, male only, with Prostatic Neoplasms or Neoplasm Metastasis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this study is to evaluate the role of local treatment with radical prostatectomy in patients with newly-diagnosed metastatic hormone-sensitive prostate cancer.

Publications & conference data

7 peer-reviewed publications reference this trial (live from Europe PMC):

  1. The Role of Cytoreductive Radical Prostatectomy in the Treatment of Newly Diagnosed Low-volume Metastatic Prostate Cancer. Results from the Local Treatment of Metastatic Prostate Cancer (LoMP) Registry.
    Lumen N, De Bleser E, Buelens S, Verla W, et al · · 2021 · cited 34× · PMID 34337536 · DOI 10.1016/j.euros.2021.05.006
  2. Whole Slide Imaging-Based Prediction of TP53 Mutations Identifies an Aggressive Disease Phenotype in Prostate Cancer.
    Pizurica M, Larmuseau M, Van der Eecken K, de Schaetzen van Brienen L, et al · · 2023 · cited 20× · PMID 37352385 · DOI 10.1158/0008-5472.can-22-3113
  3. Multicentre, prospective study on local treatment of metastatic prostate cancer (LoMP study).
    Buelens S, Poelaert F, Claeys T, De Bleser E, et al · · 2022 · cited 20× · PMID 34289231 · DOI 10.1111/bju.15553
  4. Treatment of Oligometastatic Hormone-Sensitive Prostate Cancer: A Comprehensive Review.
    Koo KC, Dasgupta P. · · 2018 · cited 14× · PMID 29869454 · DOI 10.3349/ymj.2018.59.5.567
  5. Effect on Overall Survival of Locoregional Treatment in a Cohort of De Novo Metastatic Prostate Cancer Patients: A Single Institution Retrospective Analysis From the Royal Marsden Hospital.
    Bianchini D, Lorente D, Rescigno P, Zafeiriou Z, et al · · 2017 · cited 13× · PMID 28571827 · DOI 10.1016/j.clgc.2017.04.013
  6. Oligometastatic prostate cancer: definition and the role of local and systemic therapy: a narrative review.
    Mahjoub S, Heidenreich A. · · 2021 · cited 9× · PMID 34430419 · DOI 10.21037/tau-20-1033
  7. Multifocal cohort analysis unveils cell types associated with regional lymph node seeding in prostate cancer.
    de Schaetzen van Brienen L, Jung T, Larmuseau M, Van der Eecken K, et al · · 2026 · PMID 41787470 · DOI 10.1186/s13073-026-01616-y

Verify or expand the search:

Other recruiting trials for Prostatic Neoplasms

Currently open trials in the same condition.

Other University Hospital, Ghent trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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