NCT02136810

Perioperative Blood Pressures and Chronic Hypertension

Completed Results posted Last updated 5 June 2023

What this trial tests

trial in Hypertension in 200 participants. Completed in 16 January 2018.

Timeline

9 November 2015

Primary endpoint
11 January 2017

16 January 2018

Quick facts

Lead sponsor	Yale University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	200
Start date	9 November 2015
Primary completion	11 January 2017
Estimated completion	16 January 2018
Sites	1 location across United States

Conditions studied

• Hypertension — all drugs for Hypertension →

Sponsor

Yale University

Who can join

21 and older, any sex, with Hypertension. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Performance of Blood Pressure Referral Threshold Primary · Subjects followed for approximately 1 year

The positive predictive value of preadmission testing-measured blood pressure to predict mean home blood pressure \>135/85mmHg will be calculated.

Group	Value	95% CI
Included Participants	.841	.78 – .89

Patient Perspectives and Beliefs Regarding Blood Pressure Status as They Relate to Actual Home Blood Pressures. Secondary · Approximately 60 days

In secondary analyses, the agreement between patients' self-reported blood pressure control (binary outcome) and home blood pressure monitor-determined blood pressure status (binary outcome) will we assessed via Cohen's kappa and raw indices of agreement.

Group	Value	95% CI
Included Participants	.158	.062 – .254

Sponsor's own description

This study aims to assess the performance of presurgical clinic blood pressure measurements in predicting home blood pressure readings among surgical patients. It also aims to measure the association between home blood pressures and patient perspectives on blood pressure control.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Elevated preoperative blood pressures in adult surgical patients are highly predictive of elevated home blood pressures.
   Schonberger RB, Nwozuzu A, Zafar J, Chen E, et al · · 2018 · cited 12× · PMID 29486981 · DOI 10.1016/j.jash.2018.01.012