Last reviewed · How we verify
NCT02127073
Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer
Phase 2 trial testing Intranasal Oxytocin in Breast Cancer in 8 participants. Terminated before completion.
18 January 2017
Quick facts
| Lead sponsor | Montefiore Medical Center |
|---|---|
| Phase | Phase 2 |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 8 |
| Start date | 30 January 2015 |
| Primary completion | 18 January 2017 |
| Estimated completion | 18 September 2017 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Intranasal Oxytocin — full drug profile →
Conditions studied
- Breast Cancer — all drugs for Breast Cancer →
- Ductal Carcinoma in Situ — all drugs for Ductal Carcinoma in Situ →
Sponsor
Montefiore Medical Center
Who can join
18 and older, female only, with Breast Cancer or Ductal Carcinoma in Situ. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to examine the genetic material called microRNA of three types of specimens from women with breast cancer. The study also seeks to examine the effectiveness of using a new agent called oxytocin to increase the amount of nipple fluid that can be collected during surgery.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications.
Rahbarghazi R, Jabbari N, Sani NA, Asghari R, et al · · 2019 · cited 160× · PMID 31291956 · DOI 10.1186/s12964-019-0390-y -
Targeting miRNAs and Other Non-Coding RNAs as a Therapeutic Approach: An Update.
Bayraktar E, Bayraktar R, Oztatlici H, Lopez-Berestein G, et al · · 2023 · cited 51× · PMID 37104009 · DOI 10.3390/ncrna9020027 -
MicroRNAs in cancer therapeutics: "from the bench to the bedside".
Monroig-Bosque Pdel C, Rivera CA, Calin GA, Calin GA. · · 2015 · cited 34× · PMID 26372796 · DOI 10.1517/14712598.2015.1074999 -
Non-Coding RNAs in Breast Cancer: Diagnostic and Therapeutic Implications.
Beňačka R, Szabóová D, Guľašová Z, Hertelyová Z. · · 2024 · cited 7× · PMID 39795985 · DOI 10.3390/ijms26010127
Verify or expand the search:
- PubMed search for NCT02127073
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Intranasal Oxytocin
Trials testing the same drug.
- NCT05920707 — Common and Differentiated Representations Between Social Exclusion and Social Separation · NA · unknown
- NCT05432089 — The Effects of Oxytocin Administration to Patients and Therapists on Physiological Synchronization · Phase 2 · recruiting
- NCT05532501 — The Effects of Intranasal and Oral Administration of Oxytocin on Responses to Emotional Scenes · NA · unknown
- NCT03593473 — Inhaled Oxytocin and HPA Axis Reactivity · Phase 2 · completed
- NCT02985749 — A Study of Oxytocin for the Treatment of Social Impairment in Individuals With High Functioning Autism Spectrum Disorder · Phase 3 · completed
Other recruiting trials for Breast Cancer
Currently open trials in the same condition.
- NCT06148038 — CBD for Breast Cancer Primary Tumors · Phase 1 · recruiting
- NCT07405801 — A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus R · Phase 2 · recruiting
- NCT07285993 — Detection and Outcomes in Metastatic Invasive Lobular Breast Cancer Through Novel F-18 FAP PET · Phase 2 · recruiting
- NCT07510698 — Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer · NA · recruiting
- NCT06768931 — Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer · Phase 2 · recruiting
Other Montefiore Medical Center trials
Trials by the same sponsor.
- NCT07224061 — Promoting Asthma Management Guidelines With Technology-Based Intervention and Care Coordination in Clinics and Schools · NA · not yet recruiting
- NCT06775886 — Effect of Personalized Accelerated Pacing in Symptomatic Patients With Non-Obstructive Hypertrophic Cardiomyopathy · NA · terminated
- NCT06919094 — A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults · NA · recruiting
- NCT07076069 — The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair · Phase 4 · recruiting
- NCT07037940 — Physician Response Evaluation With Contextual Insights vs. Standard Engines - Artificial Intelligence RAG vs LLM Clinica · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02127073 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Montefiore Medical Center
- Last refreshed: 9 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02127073.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing