NCT02115776 is a NA clinical trial of Amoxicillin-Potassium Clavulanate in Bacteremia, sponsored by University of Santiago de Compostela.

Who is sponsoring NCT02115776?

NCT02115776 is sponsored by University of Santiago de Compostela.

What drugs are being tested in NCT02115776?

Interventions in NCT02115776: Amoxicillin-Potassium Clavulanate, Amoxicillin, Chlorhexidine.

What condition does NCT02115776 study?

NCT02115776 studies Bacteremia.

Is NCT02115776 still recruiting?

NCT02115776 is currently completed. Last updated 26 May 2015.

Last reviewed 2015-05-26 · How we verify

NCT02115776

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures

Completed NA Last updated 26 May 2015

What this trial tests

NA trial testing Amoxicillin-Potassium Clavulanate in Bacteremia in 266 participants. Completed in 1 May 2015.

Timeline

1 January 2014

Primary endpoint
1 April 2015

1 May 2015

Quick facts

Lead sponsor	University of Santiago de Compostela
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	266
Start date	1 January 2014
Primary completion	1 April 2015
Estimated completion	1 May 2015
Sites	2 locations across Spain

Drugs / interventions tested

Amoxicillin-Potassium Clavulanate
Amoxicillin (amoxicillin) — full drug profile →
Chlorhexidine (CHLORHEXIDINE) — full drug profile →

Conditions studied

Bacteremia — all drugs for Bacteremia →

Sponsor

University of Santiago de Compostela

Who can join

Adults 18 to 65, any sex, with Bacteremia. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Number of participants receiving a prophylactic dosage with amoxicillin-clavulanate i.v. with bacteremia following dental extractions
Time frame: Changes from baseline in prevalence of bacteremia at 30 seconds, 15 minutes and 1 hour after the final dental extraction
Percentage of participants receiving a prophylactic dosage with amoxicillin-clavulanate i.v. with bacteremia confirmed by microbiological analysis at 30 seconds, 15 minutes and 1 hour after the final dental extraction

Sponsor's own description

The aim of this study is to evaluate the efficacy of prophylactic dosage with amoxicillin (AMX), amoxicillin-clavulanate (AMX-CLV), and a combination of amoxicillin-clavulanate and a chlorhexidine mouthwash (AMX-CLV-CHX) in the prevention of bacteremia following dental extractions. The study hypothesis is that an antimicrobial regimen with amoxicillin-clavulanate will show higher effectiveness in reducing the prevalence and duration of bacteremia following dental extractions, than that achieved with the classical amoxicillin regimen.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Intravenous amoxicillin/clavulanate for the prevention of bacteraemia following dental procedures: a randomized clinical trial.
Limeres Posse J, Álvarez Fernández M, Fernández Feijoo J, Medina Henríquez J, et al · · 2016 · cited 26× · PMID 27029851 · DOI 10.1093/jac/dkw081

Verify or expand the search:

Other trials of Amoxicillin-Potassium Clavulanate

Trials testing the same drug.

NCT02783404 — An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures · Phase 4 · terminated

Other recruiting trials for Bacteremia

Currently open trials in the same condition.

NCT07134751 — Febrile Infants Swedish Study · recruiting
NCT07126106 — Prospective Validation of GRADY: A Machine Learning Model for Early Sepsis and Bacteremia Detection in ICU Patients · recruiting
NCT06821282 — Surveillance of AMR in DRC · recruiting
NCT06425367 — Impact of Performing a Rapid Antibiotic Susceptibility Test on Antibiotic Therapy Adaptation in Adult Patients with Ente · NA · recruiting
NCT07486362 — Evaluation of Emergency Medicine Pharmacist Impact on Blood Culture Review Following Emergency Department Discharge · recruiting

Other University of Santiago de Compostela trials

Trials by the same sponsor.

NCT07466004 — PERMA-Based Mobile Psychological Intervention With and Without Telephone Support for University Students · NA · not yet recruiting
NCT07343284 — Nursing Health Education to Improve Functionality and Quality of Life After Ischemic Stroke · NA · not yet recruiting
NCT07430748 — REGENFAST vs L-PRF in Periodontal Regeneration · EARLY_PHASE1 · active not recruiting
NCT07355673 — The Influence of Isolation Techniques in Gingival Irritation During an In-office Bleaching · NA · completed
NCT07355647 — Efficacy of a Desensitizing Agent During In-Office Bleaching · EARLY_PHASE1 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02115776 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Santiago de Compostela
Last refreshed: 26 May 2015

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02115776.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing