Efficacy of the Combination Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: a Randomized Clinical Trial.

NCT02110966 Phase 4 COMPLETED

The purpose of this study is to evaluate the success of inferior alveolar nerve block, after the local application of Mepivacaine plus Tramadol in patients with symptomatic irreversible pulpitis. Also, to evaluate the duration of the anesthetic effect when using Mepivacaine plus Tramadol in the same anesthetic technique and patients group. Hypothesis: Local application of mepivacaine plus tramadol increases the successful of inferior alveolar nerve block in patients with irreversible pulpitis.

Details

Lead sponsor	Daniel Chavarría Bolaños
Phase	Phase 4
Status	COMPLETED
Enrolment	56
Start date	2014-04
Completion	2014-10

Conditions

• Symptomatic Irreversible Pulpitis

Interventions

• Mepivacaine
• Mepivacaine plus Tramadol

Primary outcomes

• success of the inferior alveolar nerve block — 0-30 minutes
  The anesthetic blockade will be assessed by a three step examination: lip numbess, positive/negative response to cold testing and clinical discomfort during endodontic access. Inferior alveolar nerve block success will be defined as the absence of pain during any of these evaluations and if patients report pain an analogue visual scale will be used. Also, the patient will reported the level of pain in the application of the inferior alveolar nerve block using mepivacaine and mepivacaine plus tramadol and local and systemic side effects will be monitored.

Countries

Mexico