NCT02078089 is a Phase 1 clinical trial of Morphine in Cancer, sponsored by Costantine Albany.

Who is sponsoring NCT02078089?

NCT02078089 is sponsored by Costantine Albany.

What drugs are being tested in NCT02078089?

Interventions in NCT02078089: Morphine, Oxcarbazepine.

Is NCT02078089 still recruiting?

NCT02078089 is currently terminated. Last updated 31 January 2017.

Last reviewed 2017-01-31 · How we verify

NCT02078089

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Oxcarbazepine Plus Morphine in Patients With Refractory Cancer Pain

Terminated Phase 1 Last updated 31 January 2017

What this trial tests

Phase 1 trial testing Morphine in Cancer in 1 participant. Terminated before completion.

Timeline

6 March 2014

Primary endpoint
11 December 2014

11 December 2014

Quick facts

Lead sponsor	Costantine Albany
Phase	Phase 1
Status	Terminated
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	supportive care
Enrollment	1
Start date	6 March 2014
Primary completion	11 December 2014
Estimated completion	11 December 2014
Sites	2 locations across United States

Drugs / interventions tested

Morphine
Oxcarbazepine — full drug profile →

Conditions studied

Cancer — all drugs for Cancer →

Sponsor

Costantine Albany

Who can join

18 and older, any sex, with Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is an open-label, single arm, Phase Ib dose escalation study of Oxcarbazepine with morphine in patients with refractory cancer pain. The primary endpoint is to evaluate the safety and toxicity of the combination of Oxcarbazepine plus morphine. The secondary endpoints are improving pain control, reduce morphine use and improve the quality of life.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain.
Due MR, Yang XF, Allette YM, Randolph AL, et al · · 2014 · cited 15× · PMID 25221944 · DOI 10.1371/journal.pone.0107399

Verify or expand the search:

Other trials of Morphine

Trials testing the same drug.

NCT06315920 — Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department · Phase 3 · not yet recruiting
NCT07491146 — Phase II Clinical Study of the Efficacy and Safety of HSK55718 in the Treatment of Abdominal Postoperative Pain · Phase 2 · not yet recruiting
NCT07412223 — Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery · Phase 4 · not yet recruiting
NCT07246785 — Anrikefon-based Patient-controlled Intravenous Analgesia After Laparoscopic Surgery · Phase 4 · terminated
NCT07201272 — Transversalis Fascia Plane Block Versus Intrathecal Morphine for Postoperative Analgesia in Total Abdominal Hysterectomy · NA · recruiting

Other recruiting trials for Cancer

Currently open trials in the same condition.

NCT07390045 — Exercise and Cognitive Rehabilitation Interventions for Older Cancer Survivors · NA · recruiting
NCT07528547 — Hypersight and Ethos In Pediatric Radiotherapy · NA · recruiting
NCT07481890 — Feasibility and Efficacy of the EMDR Toolbox Method in Cancer Patients. · NA · recruiting
NCT07402057 — Implementation and Evaluation of a Program Aimed at Facilitating Palliative Care Conversations · NA · recruiting
NCT07305740 — On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety · NA · recruiting

Other Costantine Albany trials

Trials by the same sponsor.

NCT02677727 — Study of Cisplatin-Induced Peripheral Neuropathy in Patients With Germ Cell Tumor · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02078089 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Costantine Albany
Last refreshed: 31 January 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02078089.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing