NCT02073773 is a Phase 3 clinical trial of Levodopa in Ischaemic Stroke, sponsored by Singapore General Hospital.

Who is sponsoring NCT02073773?

NCT02073773 is sponsored by Singapore General Hospital.

What drugs are being tested in NCT02073773?

Interventions in NCT02073773: Levodopa, Virtual Reality based therapy.

What condition does NCT02073773 study?

NCT02073773 studies Ischaemic Stroke.

Is NCT02073773 still recruiting?

NCT02073773 is currently completed. Last updated 8 February 2017.

Last reviewed 2017-02-08 · How we verify

NCT02073773

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Combinational Rehabilitative Therapy and Functional Brain Imaging for Patients Recovering From Motor Stroke

Completed Phase 3 Last updated 8 February 2017

What this trial tests

Phase 3 trial testing Levodopa in Ischaemic Stroke in 9 participants. Completed in 1 November 2015.

Timeline

1 January 2014

Primary endpoint
1 November 2015

1 November 2015

Quick facts

Lead sponsor	Singapore General Hospital
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	9
Start date	1 January 2014
Primary completion	1 November 2015
Estimated completion	1 November 2015
Sites	1 location across Singapore

Drugs / interventions tested

Levodopa (LEVODOPA) — full drug profile →
Virtual Reality based therapy

Conditions studied

Ischaemic Stroke — all drugs for Ischaemic Stroke →

Sponsor

Singapore General Hospital

Who can join

Adults 25 to 99, any sex, with Ischaemic Stroke. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Changes in the Fugl Meyer Upper Limb score at the start and end of the two weeks trial period
Time frame: At the start and end of the 2 weeks period of trial therapy
Fugl Meyer Upper Extremity Scale (FM) - a clinical assessment of upper limb tone, power and movement.

Sponsor's own description

The present proposal aims to assess whether a combined rehabilitation approach using virtual reality based therapy with motivational feedback, levodopa for pharmacotherapy and standard rehabilitative occupational therapy and physiotherapy will lead to signifcantly better outcomes for stroke recovery. It is a randomised controlled trial with blinding of the assessors only. It will be preceeded by a Phase 1 pilot trial of the VR physiotherapy and standard therapy only. Recruited in-patient rehabilitation ward patients who have recently suffered stroke will be randomized, through a computer-based random number generator, to either one of two treatment arms: 1. Control occupational therapy + pharmacotherapy for 2 weeks 2. Assisted Virtual-Reality physiotherapy + pharmacotherapy for 2 weeks

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Levodopa

Trials testing the same drug.

NCT06115538 — Comparison of Dopamin Level in Idiopathic Parkinson's Patients · Phase 4 · unknown
NCT07444892 — Levodopa for Diabetic Retinopathy · Phase 2 · completed
NCT05901350 — The Correlation of Reduction of Levodopa and Non-motor Symptoms of Parkinson's Disease After Deep Brain Stimulation · NA · completed
NCT06275633 — Behavioural Profiling of Disease-related Cognitive and Motor Impairment in PD · NA · completed
NCT03205956 — Measuring Parkinson's Disease Progression · Phase 1 · completed

Other recruiting trials for Ischaemic Stroke

Currently open trials in the same condition.

NCT07197996 — The RETRAIN Trial Phase 2 · NA · recruiting
NCT06987643 — A Clinical Study to Investigate the Effect of Oral Neflamapimod on Motor Recovery After Acute Ischaemic Stroke · Phase 2 · recruiting
NCT06940635 — Exploratory Study on the Potential Cross-System Effects of BCI-FES Hand Therapy on Dysphagia and Aphasia in Chronic Stro · NA · recruiting
NCT05922540 — a Cohort Study of Ischemic Cerebrovascular Disease · recruiting

Other Singapore General Hospital trials

Trials by the same sponsor.

NCT07452159 — Diabetes In Asians at Risk in Youth · not yet recruiting
NCT07527247 — Improving Vaccine Protection for Older Adults · Phase 2 · recruiting
NCT07533188 — Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomize · NA · recruiting
NCT07042061 — Trial of Mobile External Defibrillator for Out-of-hospital Cardiac Arrest in Singapore. · NA · not yet recruiting
NCT07099040 — Community-based Multi-domain Intervention to Detect and Delay Cognitive Decline in Community-dwelling Older Adults: A Pi · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02073773 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Singapore General Hospital
Last refreshed: 8 February 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02073773.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing