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NCT02060266

Trial Investigating the Absorption, Metabolism and Excretion After a Single Subcutaneous Dose of [3H]-Semaglutide in Healthy Male Subjects

Completed Phase 1 Last updated 28 March 2017
What this trial tests

Phase 1 trial testing semaglutide in Diabetes in 7 participants. Completed in 28 April 2014.

Timeline
4 February 2014
Primary endpoint
28 April 2014
28 April 2014

Quick facts

Lead sponsorNovo Nordisk A/S
PhasePhase 1
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment7
Start date4 February 2014
Primary completion28 April 2014
Estimated completion28 April 2014
Sites1 location across Netherlands

Drugs / interventions tested

Conditions studied

Sponsor

Novo Nordisk A/S — full company profile →

Who can join

Adults 45 to 64, male only, with Diabetes or Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This trial is conducted in Europe. The aim of the trial is to investigate the absorption, metabolism and excretion after a single subcutaneous dose of \[3H\]-semaglutide in healthy male subjects.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species.
    Jensen L, Helleberg H, Roffel A, van Lier JJ, et al · · 2017 · cited 120× · PMID 28323117 · DOI 10.1016/j.ejps.2017.03.020
  2. Semaglutide, a glucagon like peptide-1 receptor agonist with cardiovascular benefits for management of type 2 diabetes.
    Mahapatra MK, Karuppasamy M, Sahoo BM. · · 2022 · cited 92× · PMID 34993760 · DOI 10.1007/s11154-021-09699-1

Verify or expand the search:

Other trials of semaglutide

Trials testing the same drug.

Other recruiting trials for Diabetes

Currently open trials in the same condition.

Other Novo Nordisk A/S trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02060266.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing