Incremental Utility of Myocardial Contrast Echocardiography for the Assessment of the Infarct Related Artery and Risk Area in Patients With Non-ST Segment Elevation Myocardial Infarction.

NCT02014701 NA UNKNOWN

The goal of this study will be to assess the incremental benefit of myocardial contrast echocardiography for the assessment of regional wall motion abnormalities and infarct-related artery in patients presenting with their first NSTEMI.

Details

Lead sponsor	Cedars-Sinai Medical Center
Phase	NA
Status	UNKNOWN
Enrolment	100
Start date	2012-08
Completion	2014-03

Conditions

• STEMI

Interventions

• Echocardiogram

Primary outcomes

• Accuracy of determination of the infarct related artery as compared to the findings from clinically indicated coronary angiography — Baseline: Immediately following resting echocardiogram at time of index STEMI and prior to cardiac cath.
  Patients presenting with NSTEMI who are scheduled to undergo elective cardiac catheterization and coronary angiography with primary PCI will be selected for participation in the study. The patients will undergo a clinically indicated resting non-contrast echocardiogram to assess LV function and regional wall motion. Immediately following, they will then undergo contrast echocardiography with bolus injection of Optison™ contrast to reassess LV ejection fraction, improve LV opacification and assess regional wall motion abnormalities. Finally, they will be given a continuous infusion of Optison™ and will have assessment of myocardial perfusion of each of the 17 myocardial segments using low mechanical index continuous imaging of the myocardium and blood pool.

Countries

United States