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NCT02012933

3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenia (CM)

NO LONGER AVAILABLE Last updated 11 December 2019
What this trial tests

trial testing 3,4-diaminopyridine in Lambert-Eaton Myasthenic Syndrome (LEMS). No longer available.

Quick facts

Lead sponsorOregon Health and Science University
StatusNO LONGER AVAILABLE
Study typeEXPANDED_ACCESS
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Oregon Health and Science University

Who can join

2 and older, any sex, with Lambert-Eaton Myasthenic Syndrome (LEMS) or Congenital Myasthenia (CM). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Lambert-Eaton Myasthenic Syndrome (LEMS) is a rare autoimmune disorder which affects the nerve-muscle junction. The major symptoms of LEMS are progressive muscle weakness. Many patients experience other symptoms like dry mouth or impotence. Congenital Myasthenia (CM) is an inherited disorder with similar affects and symptoms. 3,4-Diaminopyridine (DAP) is an experimental drug that has improved strength in some subjects with (LEMS). There are no other accepted treatments for LEMS and DAP has relatively few side effects.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other trials of 3,4-diaminopyridine

Trials testing the same drug.

Other Oregon Health and Science University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02012933.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing