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A Randomized, Parallel-Group Comparison Study of Topical Corticosteroids in Dry Eye Patients With Sjögren Syndrome
The purpose of this study is to evaluate the effectiveness of fluorometholone combined with sodium hyaluronate eye drops in the treatment of Sjögren syndrome.
Details
| Lead sponsor | Santen Pharmaceutical(China) Co.,LTD |
|---|---|
| Status | COMPLETED |
| Enrolment | 35 |
| Start date | 2013-03 |
| Completion | 2013-11 |
Conditions
- Dry Eye Syndromes
- Sjögren Syndrome
Primary outcomes
- tear-film breakup time — the enrolling day,2 weeks after treatment,4 weeks after treatment,8 weeks after treatment
stain the cornea with the fluorescein; close the eye; open the eye and keep the eye open,count the seconds until the first black spot appears. - Schirmer test I without anesthesia — the enrolling day,2 weeks after treatment,4 weeks after treatment, 8 weeks after treatment
put the Schirmer test strip into the lower conjunctival sac; close the eye for 5 minutes; read the score of the test strip - corneal fluorescein staining — the enrolling day,2 weeks after treatment,4 weeks after treatment,8 weeks after treatment
Fluorescein staining scores were measured on 0-3 point scale, in each quarter of corneal zone: 0(No staining), 1(some staining), 2(Staining in more than a half of the area), 3(Staining in the whole area).
Countries
China