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NCT02007421: SPANC

Study of the Prevention of Anal Cancer

Completed NA Last updated 2 December 2019
What this trial tests

NA trial testing Participants asked questions about recent experiences of anal intercourse in the last six months. in Human Papillomavirus in 617 participants. Completed in 4 December 2018.

Timeline
10 September 2010
Primary endpoint
4 May 2018
4 December 2018

Quick facts

Lead sponsorKirby Institute
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designsingle group
Maskingnone
Primary purposeprevention
Enrollment617
Start date10 September 2010
Primary completion4 May 2018
Estimated completion4 December 2018
Sites2 locations across Australia

Drugs / interventions tested

Conditions studied

Sponsor

Kirby Institute

Who can join

35 and older, male only, with Human Papillomavirus or Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

SPANC stands for Study of the Prevention of Anal Cancer. There are more than 100 types of human papillomavirus (HPV). Some HPV types cause genital warts and other types cause more than 90% of anal cancer. Gay men are over 20 times more likely than others to develop anal cancer. SPANC is a study of anal (HPV) infection and related anal disease in gay men. The study will provide important information to guide the possible future introduction of anal cancer screening programs for gay men.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Screening for Anal Cancer in Women.
    Moscicki AB, Darragh TM, Berry-Lawhorn JM, Roberts JM, et al · · 2015 · cited 90× · PMID 26103446 · DOI 10.1097/lgt.0000000000000117
  2. Human papillomavirus 16-specific T-cell responses and spontaneous regression of anal high-grade squamous intraepithelial lesions.
    Tong WW, Shepherd K, Garland S, Meagher A, et al · · 2015 · cited 27× · PMID 25139018 · DOI 10.1093/infdis/jiu461
  3. Effect of Human Papillomavirus Vaccine to Interrupt Recurrence of Vulvar and Anal Neoplasia (VIVA): A Trial Protocol.
    Stankiewicz Karita HC, Hauge K, Magaret A, Mao C, et al · · 2019 · cited 23× · PMID 30977845 · DOI 10.1001/jamanetworkopen.2019.0819

Verify or expand the search:

Other recruiting trials for Human Papillomavirus

Currently open trials in the same condition.

Other Kirby Institute trials

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02007421.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing