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NCT02007421: SPANC
Study of the Prevention of Anal Cancer
NA trial testing Participants asked questions about recent experiences of anal intercourse in the last six months. in Human Papillomavirus in 617 participants. Completed in 4 December 2018.
4 May 2018
Quick facts
| Lead sponsor | Kirby Institute |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | single group |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 617 |
| Start date | 10 September 2010 |
| Primary completion | 4 May 2018 |
| Estimated completion | 4 December 2018 |
| Sites | 2 locations across Australia |
Drugs / interventions tested
- Participants asked questions about recent experiences of anal intercourse in the last six months.
- High Resolution Anoscopy
Conditions studied
- Human Papillomavirus — all drugs for Human Papillomavirus →
- Cancer — all drugs for Cancer →
Sponsor
Kirby Institute
Who can join
35 and older, male only, with Human Papillomavirus or Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
SPANC stands for Study of the Prevention of Anal Cancer. There are more than 100 types of human papillomavirus (HPV). Some HPV types cause genital warts and other types cause more than 90% of anal cancer. Gay men are over 20 times more likely than others to develop anal cancer. SPANC is a study of anal (HPV) infection and related anal disease in gay men. The study will provide important information to guide the possible future introduction of anal cancer screening programs for gay men.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Screening for Anal Cancer in Women.
Moscicki AB, Darragh TM, Berry-Lawhorn JM, Roberts JM, et al · · 2015 · cited 90× · PMID 26103446 · DOI 10.1097/lgt.0000000000000117 -
Human papillomavirus 16-specific T-cell responses and spontaneous regression of anal high-grade squamous intraepithelial lesions.
Tong WW, Shepherd K, Garland S, Meagher A, et al · · 2015 · cited 27× · PMID 25139018 · DOI 10.1093/infdis/jiu461 -
Effect of Human Papillomavirus Vaccine to Interrupt Recurrence of Vulvar and Anal Neoplasia (VIVA): A Trial Protocol.
Stankiewicz Karita HC, Hauge K, Magaret A, Mao C, et al · · 2019 · cited 23× · PMID 30977845 · DOI 10.1001/jamanetworkopen.2019.0819
Verify or expand the search:
- PubMed search for NCT02007421
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Human Papillomavirus
Currently open trials in the same condition.
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- NCT06434337 — Evaluation of a Novel Point-of-Care Diagnostic Test for Human Papillomavirus (HPV) · recruiting
- NCT05365048 — Provider Recommendation and HPV Vaccination · NA · recruiting
- NCT05026138 — Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune) · recruiting
- NCT04708470 — A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, · Phase 1, PHASE2 · active not recruiting
Other Kirby Institute trials
Trials by the same sponsor.
- NCT07145736 — Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical · Phase 4 · recruiting
- NCT06220370 — PATH Study: People With Injecting Related Infections: Assessing Treatment Outcomes for Those Who Are Hospitalised. · not yet recruiting
- NCT05415267 — Immunosuppression and COVID-19 Boosters · Phase 3 · recruiting
- NCT05144776 — Evaluation of Hepatitis B Virus (HBV) DNA Test As Point of Care Tool · completed
- NCT04014179 — Enhancing Hepatitis C Testing and Treatment Among People Who Inject Drugs Attending Needle and Syringe Programs · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02007421 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kirby Institute
- Last refreshed: 2 December 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02007421.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing