Last reviewed · How we verify
Efficacy and Safety of FTY720 for the Treatment of Acute Stroke
Stroke is one of the main severe disease of public health importance. Increasing evidence suggests that inflammatory mechanisms plays a significant role in stroke. So, immune targets are supposed to be an effective one. The sphingosine-1-phosphate receptor regulator Fingolimod(FTY720)is an effective immunology modulator which has been widely used in autoimmune disease and has been testified effective on stoke animal models.
Details
| Lead sponsor | Tianjin Medical University General Hospital |
|---|---|
| Phase | Phase 2 |
| Status | COMPLETED |
| Enrolment | 22 |
| Start date | 2012-10 |
| Completion | 2014-10-01 |
Conditions
- Stroke
- Vascular Accident
- Cerebral Stroke
- Ischemic Cerebrovascular Accident
- Stroke, Acute
Interventions
- Fingolimod
Primary outcomes
- Clinical improvement — up to 90 days
Neurofunctional assessment including NIHSS, modified Barthel Index, modified Rankin Scale,and Glasgow coma scale are used to describe the clinical improvement at baseline, 7days, 14days, 30days and 90days.
Countries
China