Who is sponsoring NCT01999647?

NCT01999647 is sponsored by University of Parma.

What drugs are being tested in NCT01999647?

Interventions in NCT01999647: Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block, Patient-Controlled Postoperative Analgesia, Ropivacaine.

What condition does NCT01999647 study?

NCT01999647 studies Orthopedic Disorders, Foot Diseases, Injuries, Leg, Injuries, Foot, Injuries, Knee.

Is NCT01999647 still recruiting?

NCT01999647 is currently completed. Last updated 2 December 2013.

Last reviewed 2013-12-02 · How we verify

NCT01999647

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intraneural Injection of Ropivacaine for Subgluteal Sciatic Nerve Block Leads to Faster Onset and Higher Success Rates: a Randomized, Controlled Trial

Completed NA Last updated 2 December 2013

What this trial tests

NA trial testing Intraneural Injection for Subgluteal Sciatic Nerve Block in Orthopedic Disorders in 64 participants. Completed in 1 December 2012.

Timeline

1 December 2011

Primary endpoint
1 September 2012

1 December 2012

Quick facts

Lead sponsor	University of Parma
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	64
Start date	1 December 2011
Primary completion	1 September 2012
Estimated completion	1 December 2012
Sites	1 location across Italy

Drugs / interventions tested

Intraneural Injection for Subgluteal Sciatic Nerve Block
Perineural Injection for Subgluteal Sciatic Nerve Block
Femoral Nerve Block — full drug profile →
Patient-Controlled Postoperative Analgesia
Ropivacaine (ROPIVACAINE) — full drug profile →

Conditions studied

Orthopedic Disorders — all drugs for Orthopedic Disorders →
Foot Diseases — all drugs for Foot Diseases →
Injuries, Leg — all drugs for Injuries, Leg →
Injuries, Foot — all drugs for Injuries, Foot →

Sponsor

University of Parma

Who can join

18 and older, any sex, with Orthopedic Disorders or Foot Diseases. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Onset Time of Sciatic Nerve Block
Time frame: ≤30 minutes after block performance
Time to onset of sciatic nerve anesthesia, defined as both following criteria: * Sensory: does not feel pain or discomfort when pricked with a 25G needle. * Motor: able to slightly curl toes; unable to flex the ankle.

Sponsor's own description

This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), requires a shorter time to develop surgical anesthesia of the lower leg. The investigators will compare the two types of injection using the same drug, so as to determine if there is an actual difference onset time. They will also examine the overall success rate of either kind of sciatic nerve blocks as the sole anesthetic for non-emergent orthopedic surgery. The safety of these procedures will be examined by in-hospital and phone-call follow-up contacts.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other University of Parma trials

Trials by the same sponsor.

NCT07242079 — Effect Of Pulmonary Rehabilitation in Patients With Alpha-1 Antitrypsin Deficiency · completed
NCT06977802 — Design and Implementation of a Mobile App for Promoting Healthy and Sustainable Eating Among Students at the University · NA · completed
NCT06347094 — Precision Nutrition to Improve Cardiometabolic Health With Dietary (Poly)Phenols · NA · recruiting
NCT06028659 — Investigation of in Vivo Endogenous and/or Exogenous Production of Phenolic Metabolites Using (un)Targeted Metabolomics · NA · recruiting
NCT06455956 — Use of miRNAs in Growth Hormone Deficiency (GHD) · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01999647 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Parma
Last refreshed: 2 December 2013

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01999647.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing