Last reviewed · How we verify
NCT01956500
Influence of Instaflex Joint Support Supplement on Joint Pain, Stiffness, Function, and Inflammation: a Randomized, Placebo-controlled Community Trial
NA trial testing Instaflex in Joint Pain, Stiffness, Function in 110 participants. Completed in 1 June 2013.
1 June 2013
Quick facts
| Lead sponsor | Appalachian State University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 110 |
| Start date | 1 April 2013 |
| Primary completion | 1 June 2013 |
| Estimated completion | 1 June 2013 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Instaflex
- Placebo
Conditions studied
- Joint Pain, Stiffness, Function — all drugs for Joint Pain, Stiffness, Function →
Sponsor
Appalachian State University
Who can join
Adults 50 to 75, any sex, with Joint Pain, Stiffness, Function. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Joint pain and function
Time frame: Change in joint pain and function at 8 weeks
Assessed through questionnaires
Sponsor's own description
The primary purpose of this study is to assess the effect of 8-weeks ingestion of the Instaflex Joint Support supplement (Direct Digital, Charlotte, NC) compared to placebo on joint pain, stiffness, and function (questionnaires and 6-min walk test) and blood inflammation biomarkers in adults with self-reported joint pain.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial.
Nieman DC, Shanely RA, Luo B, Dew D, et al · · 2013 · cited 30× · PMID 24274358 · DOI 10.1186/1475-2891-12-154
Verify or expand the search:
- PubMed search for NCT01956500
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Appalachian State University trials
Trials by the same sponsor.
- NCT07413874 — Telehealth Music Therapy for Adults With Endocrine Disorder and Depression · NA · not yet recruiting
- NCT06495190 — Cognition, Flavonoids, Exercise, Gut Microbiome · NA · recruiting
- NCT06392360 — Betaine, Exercise Performance, and Gut Permeability · NA · completed
- NCT06204666 — Hemp Fiber Ingestion and Gut Permeability After Exercise · NA · completed
- NCT05907135 — Beet Supplementation, Exercise, Inflammation · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01956500 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Appalachian State University
- Last refreshed: 7 October 2013
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01956500.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing