NCT01948583 (GYNOMUNAL®) is a Phase 4 clinical trial of Hyaluronic Acid in Vaginal Dryness, sponsored by Derming SRL.

Who is sponsoring NCT01948583?

NCT01948583 is sponsored by Derming SRL.

What drugs are being tested in NCT01948583?

Interventions in NCT01948583: Hyaluronic Acid.

What condition does NCT01948583 study?

NCT01948583 studies Vaginal Dryness, Menopause.

Is NCT01948583 still recruiting?

NCT01948583 is currently completed. Last updated 19 September 2013.

Last reviewed 2013-09-19 · How we verify

NCT01948583: GYNOMUNAL®

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Humectant Activity of a New Formulation of Gynomunal® Vaginalgel: Crossover Test Use Versus Previous Formula

Completed Phase 4 Last updated 19 September 2013

What this trial tests

Phase 4 trial testing Hyaluronic Acid in Vaginal Dryness in 28 participants. Completed in 1 July 2013.

Timeline

1 May 2013

Primary endpoint
1 May 2013

1 July 2013

Quick facts

Lead sponsor	Derming SRL
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	treatment
Enrollment	28
Start date	1 May 2013
Primary completion	1 May 2013
Estimated completion	1 July 2013
Sites	1 location across Italy

Drugs / interventions tested

Hyaluronic Acid (HYALURONIC ACID) — full drug profile →

Conditions studied

Vaginal Dryness — all drugs for Vaginal Dryness →
Menopause — all drugs for Menopause →

Sponsor

Derming SRL — full company profile →

Who can join

Eligibility, female only, with Vaginal Dryness or Menopause. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Vaginal Humidity determination
Time frame: 2 weeks

Sponsor's own description

Aim of the study is to evaluate the humectant activity and the local tolerability of a new formulation of Gynomunal® vaginalgel in menopausal women (menopause since at least 2 years) with referred vaginal dryness

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Hyaluronic Acid: A Valid Therapeutic Option for Early Management of Genitourinary Syndrome of Menopause in Cancer Survivors?
Nappi RE, Martella S, Albani F, Cassani C, et al · · 2022 · cited 15× · PMID 36011183 · DOI 10.3390/healthcare10081528

Verify or expand the search:

Other trials of Hyaluronic Acid

Trials testing the same drug.

NCT07501585 — Hyaluronic Acid in Endodontic Microsurgery · NA · recruiting
NCT06469216 — Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis · Phase 1, PHASE2 · completed
NCT06426199 — Chitosan-Hyaluronate Gel Mixture Vs Hyaluronic for Internal Derangement · Phase 4 · unknown
NCT02459392 — EuroPainClinics® Study II (Prospective Trial) · NA · completed
NCT05776290 — The Effect of Hyaluronic Acid Gel on Relieving Post-Implantation Pain · NA · completed

Other recruiting trials for Vaginal Dryness

Currently open trials in the same condition.

NCT07420647 — Pilot Study of Individualized Treatment for Genitourinary Syndrome of Menopause in Women After Cancer Treatment · NA · active not recruiting

Other Derming SRL trials

Trials by the same sponsor.

NCT04239768 — Efficacy of an Antiage Aesthetic Treatment for the Middle and Inferior Third of the Face · NA · completed
NCT04113265 — Aesthetic Performance of an Injective Treatment for the Inner Thighs, Knees and Arms · NA · completed
NCT04002856 — Aesthetic Performance of "Profhilo®" Injective Intradermal Treatment for the Neck · NA · completed
NCT03881189 — Efficacy and Tolerance Evaluation of an Injective Treatment for the Area Around the Eyes · NA · completed
NCT03801343 — Efficacy and Tolerance Evaluation of an Amino Acid Food Supplement · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01948583 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Derming SRL
Last refreshed: 19 September 2013

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01948583.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing