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Evaluation of Closed-loop Titration of the Intravenous Anesthetic Propofol, Sufentanil and Ketamine Guided by BIS Monitor
The purpose of this study is to compare a closed-loop intravenous anesthetic using Bispectral Index as a feedback loop and a controller based on reinforcement learning to titrate dose and intravenous anesthetic that is manually controlled or a standard volatile anesthetic agent titrated by the anesthesiologist to determine improvement in the following parameters as compared to controls: time to discharge from the Post Anesthesia Care Unit, post-operative nausea and vomiting, pain scores and sedation scores.
Details
| Lead sponsor | The University of Texas Health Science Center at San Antonio |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 4 |
| Start date | 2013-09 |
| Completion | 2014-08 |
Conditions
- Acute Cholecystitis
- Chronic Cholecystitis
Interventions
- TIVA - Hypotension
- TIVA - Hypertension
- TIVA - Bradycardia
- TIVA - Tachycardia
- INH - Hypotension
- INH - Hypertension
- INH - Bradycardia
- INH - Tachycardia
Primary outcomes
- Time to discharge from PACU — < 2 hours post operatively
Countries
United States