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NCT01939431
Genetic and Other Aspects of Podoconiosis
trial in Podoconiosis in 76 participants. Terminated before completion.
30 December 2019
Quick facts
| Lead sponsor | National Human Genome Research Institute (NHGRI) |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 76 |
| Start date | 20 August 2013 |
| Primary completion | 30 December 2019 |
| Estimated completion | 30 December 2019 |
| Sites | 1 location across Ethiopia |
Conditions studied
- Podoconiosis — all drugs for Podoconiosis →
Sponsor
National Human Genome Research Institute (NHGRI)
Who can join
Adults 18 to 70, any sex, with Podoconiosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: \- Podoconiosis is a disease of the lymph vessels in the legs and feet. It is caused by long-term barefoot exposure to irritant soils, such as those in volcanic areas. It causes severe swelling and disfigurement, as well as infection and chronic pain. It mostly affects people who live in tropical Africa, Central and South America, and India. The reasons why some people develop this disease and others do not is not well understood. Researchers want to study people with the disease and healthy volunteers in Ethiopia. They will collect skin and blood samples to study genetic and other aspects of the disease. Objectives: \- To collect skin and blood samples to study genetic and other aspects of podoconiosis. Eligibility: * Individuals at least 18 years of age who have podoconiosis (early stage or advanced stage). * Healthy volunteers at least 18 years of age. * Participants will be recruited from a study clinic and hospital in Ethiopia. Design: * Participants will be screened with a physical exam and medical history. * Blood samples will be collected. A skin biopsy will be performed to collect tissue for study. People who have podoconiosis will provide affected and unaffected tissue. Healthy volunteers will provide a single skin biopsy sample. * Treatment will not be provided as part of this study.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT01939431
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01939431 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Human Genome Research Institute (NHGRI)
- Last refreshed: 14 January 2021
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing