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NCT01937377

GLORIA-AF Registry Program (Phase II/III)

Completed Last updated 15 February 2021
What this trial tests

trial in Stroke in 200 participants. Completed in 15 April 2019.

Timeline
2 September 2013
Primary endpoint
15 April 2019
15 April 2019

Quick facts

Lead sponsorBoehringer Ingelheim
StatusCompleted
Study typeOBSERVATIONAL
Enrollment200
Start date2 September 2013
Primary completion15 April 2019
Estimated completion15 April 2019
Sites5 locations across Switzerland

Conditions studied

Sponsor

Boehringer Ingelheim — full company profile →

Who can join

18 and older, any sex, with Stroke or Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this part of the Registry Program patients with non-valvular atrial fibrillation (AF) at risk for stroke are enrolled to characterize the target population and to collect real world data on important outcome events. For administrative purposes the study is divided into three protocol numbers: 1160.129 for all non-EU (European Union) and non-EEA (European Economic Area) countries, 1160.136 for EU and EEA countries and 1160.171 for Switzerland. The total number of patients enrolled in three protocols is estimated to be 48,000 patients, and all these patients will be included in the data analysis for study 1160.129.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Evaluation of bleeding in patients receiving direct oral anticoagulants.
    Hellenbart EL, Faulkenberg KD, Finks SW. · · 2017 · cited 64× · PMID 28860793 · DOI 10.2147/vhrm.s121661
  2. Patterns of comorbidities in patients with atrial fibrillation and impact on management and long-term prognosis: an analysis from the Prospective Global GLORIA-AF Registry.
    Romiti GF, Corica B, Mei DA, Bisson A, et al · · 2024 · cited 45× · PMID 38589864 · DOI 10.1186/s12916-024-03373-4
  3. Patterns of oral anticoagulant use and outcomes in Asian patients with atrial fibrillation: a post-hoc analysis from the GLORIA-AF Registry.
    Romiti GF, Corica B, Proietti M, Mei DA, et al · · 2023 · cited 32× · PMID 37753446 · DOI 10.1016/j.eclinm.2023.102039
  4. Global Oral Anticoagulation Use Varies by Region in Patients With Recent Diagnosis of Atrial Fibrillation: The GLORIA-AF Phase III Registry.
    Bayer V, Kotalczyk A, Kea B, Teutsch C, et al · · 2022 · cited 30× · PMID 35243870 · DOI 10.1161/jaha.121.023907
  5. Changes in anticoagulant prescription patterns over time for patients with atrial fibrillation around the world.
    Kozieł M, Teutsch C, Bayer V, Lu S, et al · · 2021 · cited 29× · PMID 34386125 · DOI 10.1002/joa3.12588
  6. Incidence and Risk Factors for Residual Adverse Events Despite Anticoagulation in Atrial Fibrillation: Results From Phase II/III of the GLORIA-AF Registry.
    Ding WY, Lane DA, Gupta D, Huisman MV, et al · · 2022 · cited 28× · PMID 35876418 · DOI 10.1161/jaha.122.026410
  7. Impact of early ablation of atrial fibrillation on long-term outcomes: results from phase II/III of the GLORIA-AF registry.
    Ding WY, Calvert P, Gupta D, Huisman MV, et al · · 2022 · cited 14× · PMID 35488127 · DOI 10.1007/s00392-022-02022-1
  8. Persistence with Anticoagulation for Atrial Fibrillation: Report from the GLORIA-AF Phase III 1-Year Follow-up.
    Kozieł M, Mazurek M, Teutsch C, Diener HC, et al · · 2020 · cited 13× · PMID 32586056 · DOI 10.3390/jcm9061969

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