A Clinical Trial on Hepatitis B Vaccine Activated-DCs Combined With Peg-interferon or Nucleotide Analogs in Chronic Hepatitis B

NCT01935635 Phase 1/Phase 2 COMPLETED

The purpose of this study is to investigate whether HB-Vac Activated-DCs Combined With Peg-IFN or NAs has more efficacy than Peg-IFN or NAs alone in the treatment of chronic hepatitis B patients

Details

Lead sponsor	Third Affiliated Hospital, Sun Yat-Sen University
Phase	Phase 1/Phase 2
Status	COMPLETED
Enrolment	400
Start date	2015-01
Completion	2019-12

Conditions

• Chronic Hepatitis B

Interventions

• HPDCs-T immune therapy

Primary outcomes

• HBV makers — 01/01/2014-31/12/2016, total 6 times (3 years)
  HBV DNA loads,HBsAg/HBsAb titer,HBeAg/HBeAb titer

Countries

China